Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Microecology》 2012-04
Add to Favorite Get Latest Update

The modulation effect of different prebiotics on intestinal flora of mice with dysbacteriosis induced by antibiotics

YI An-ni1,ZHANG Hui-ye2,LIU Bing1,WEI Shuang1,ZHANG Hao-qi1,WU Xi-yang1(1.Jinan University,Institute of Technology,Food science and engineering department,Guangzhou 510632,China;2.Hutchison Whampoa Guangzhou Baiyunshan,Chinese Medicine Company Limited,Guangzhou 510000,China)  
Objective To study the impact of inulin and garlic polysaccharides on intestinal flora of mice with dysbacteriosis induced by antibiotics.Method 12 mice taken randomly from 72 SPF Balb/c mice were used as controls;The remaining 60 were given gastric perfusion of lincomycin hydrochloride and ceftriaxone sodium,twice daily,for continuous 3 days to induce mouse intestinal microdysbiosis.On the fourth day,all 60 mice were randomly divided into 5 groups-inulin,high-dose garlic polysaccharides,low-dose garlic polysaccharides,Lizhuchangle and natural recovery group,and given modulating treatment with the corresponding drugs respectively for continuous 5 days;The natural recovery group was treated with saline.Result Compared with the natural recovery group,both inulin and high-dose garlic polysaccharides groups showed their abilities to promote the growth of normal intestinal flora,improve acid content,lower the endotoxin level and effectively increase IgG level(P0.05).However,low-dose garlic polysaccharides and Lizhuchangle were less effective.Conclusion Both inulin and garlic polysaccharides at high dose have prebiotic effects on intestinal microflora imbalance induced by antibiotics in mice.
【CateGory Index】: R965
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved