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《Chinese Journal of Microecology》 2012-04
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Analysis of cinnamon oil composition and the anti-cancer effect of cinnamaldehyde

CHEN Li-ping1,ZHANG Hui-ping1,CHEN Guang2,WANG Shu-xiang2,LIU Yue-xia2,TAN Hong2,LIU Lei2(1.Jiamusi Center Hospital,Jiamusi 154002,China;2.College of Basic Medical Sciences,Jiamusi University,Jiamusi 154007,China)  
Objective To investigate the anti-tumor effect of cinnamaldehyde.Method Steam distillation method was used to extract the cinnamon oil and gas chromatography-mass spectrometry was used to analyze its compounds.MTT assay was used to test the inhibitory effect of cinnamaldehyde at different concentrations on different types of tumor cell lines in vitro.IC50 was calculated.Result The yielding rate of cinnamon oil was 1.96%.10 different compounds were analyzed,with cinnamaldehyde as the main ingredients which accounted for 93.94% of the total distillate peak area;After cinnamaldehyde treatment,the proliferation of human cervical cancer cell line HeLa,lung cancer cell line A549 and human hepatoma cell line HepG2 was blocked in a dose-dependent manner.The IC50 values of cinnamaldehyde for human cervical cancer cell line HeLa,lung cancer cell line A549 and human hepatoma cell line HepG2 were 0.20 mg/ml,0.36 mg/ml and 0.73 mg/mL respectively by MTT method.Conclusion Cinnamaldehyde has anti-tumor activity in vitro.
【CateGory Index】: R285.5
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Chinese Journal Full-text Database 6 Hits
1 ZHOU Ming;CHEN Zheng Yi;SHEN Shuting;Animal Science and Technology College,Anhui Agricultural University;Guangzhou Xinnong Feed Science and Technology Co.,Ltd.;;Manufacturing Methods and Biological Functions of Cinnamaldehyde[J];Chinese Journal of Animal Nutrition;2014-08
2 ZHOU Ming;CHEN Zheng-yi;SHEN Shu-ting;College of Animal Science and Technology,Anhui Agricultural University;Guangzhou Xinnong Biological Science and Technology Co. Ltd.;;Recent Advanceson Cinnamaldehyde[J];Journal of Economic Animal;2015-01
3 WANG Bo;GONG Wei;CHEN Guo -bao;SONG Gui -ping;JIN Jun -jie;QIN Kun -ming;CAI Bao chang;Nanjing Haichang Chinese Medicine Group Corporation;Hangzhou Haishan Pharmaceutical Equipment Limited Company;Jiangyin Chinese Medicine Hospital;Engineering Research for Standardization of Chinese Medicine Processing,National Education Department,Nanjing University of Traditional Chinese Medicine;;Gas Chromatography /Mass Spectrometry on Volatile Components of Cinnamon[J];World Journal of Integrated Traditional and Western Medicine;2014-09
4 LIU Yang;CHEN Chu-ying;CHEN Ming;QU Xue-yan;WAN Chun-peng;CHEN Jin-yin;Jiangxi Key Laboratory for Postharvest Technology and Nondestructive Testing of Fruits &Vegetables,Jiangxi Agricultural University;;Optimization of ultrasound-assisted extraction and antibacterial activity of Cinnamomi Cassiae Presl[J];Food Science and Technology;2015-06
5 ZHAO Xiu-ling(Huangshan University,Huangshan 245021,China);Research Progress on Physiologically Active Components in Cinnamomum cassia Presl[J];China Condiment;2013-03
6 HE Jun-lin,LI Ning,HE Li-ping,WEI Bing-qian(Nanning Chemical Industrial Research & Design Institute,Nanning Guangxi 530022);The integrated utilization of cinnamon oil and its further processing products[J];China Food Additives;2013-03
Chinese Journal Full-text Database 1 Hits
1 HUANG Jing-Qun~①,WANG Si-Wang,LUO Xiao-Xing~②,XIE Yan-Hua (~①Institute of Materia Medica,~②Department of Pharmacology,School of Pharmacy,Fourth Military Medical University,Xi’an 710032,Shaanxi China);Effect of Cinnamaldehyde on Proliferation and Apoptosis of a Heterologous Graft in Nude mice Bearing Human Gastric Carcinoma[J];Pharmaceutical Journal of Chinese People's Liberation Army;2006-05
Chinese Journal Full-text Database 7 Hits
1 ZHAO Meilin;HUANG Ping;The Affiliated Hospital of Stomatology to Chongqing Medical University;Chongqing Research Center for Oral Diseases and Biomedical Science;West China Hospital of Stomatology;;Effects of Cinnamic Aldehyde on Proliferation of Tongue Cancer Tca8113 Cells in Vitro[J];Western Journal of Traditional Chinese Medicine;2013-10
2 LIU Jia-bao;School of Bio-Pharmaceutical and Food Engineering,Mudanjiang University;;Determination of cinnamaldehyde content in Yougui pill by HPLC[J];Heilongjiang Science;2014-08
3 LI Ling-xu1, CHEN Yan-cui2, HAO Shuang-hong1(1.College of Chemistry and Pharmacology,Qingdao Agricultural University,Qingdao,266109,Shandong,China;2.Student of Grade 2007,Special in Pharmaeutical Engineering,Qingdao Agricultural University,Qingdao,266109,Shandong,China);Solubilization of O/W Micro-emulsion for Cinnamon Oil[J];Lishizhen Medicine and Materia Medica Research;2012-01
4 Feng Chengcheng;Zou Xi;Wu Jian;Zhou Jinyong;Wang Ruiping;The First Clinical Medical College, Nanjing University of Traditional Chinese Medicine;Jiangsu Provincial Hospital of Traditional Chinese Medicine;;Discussion on Cell Apoptosis and Its Related Molecular Mechanisms of Human Gastric Carcinoma Cell Line BGC-823 Induced by Cinnamaldehyde[J];Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology;2013-05
5 Chen Zhusheng;You Fengming;Xiao Chong;Yan Ran;Cai Yi;Yao Dejiao;Department of Oncology,Teaching Hospital of Cheng du University of Traditional Chinese Medicine;;Discuss Treatment theory of Kidney Brain and Gastric with Chemotherapy-induced Vomiting[J];World Chinese Medicine;2015-04
6 Zhang Hong;Tang Zhaohui;Li La;Cao Liang;Zhang Chenfeng;Wang Tuanjie;Ding Gang;Wang Zhenzhong;Xiao Wei;Jiangsu Kanion Pharmaceutical Co.Ltd.;State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process;;Effects on Content Changes of Main Components in Gui-Zhi Fu-Ling Capsule on Main Pharmacodynamics[J];Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology;2015-05
7 YI Xing;TAN Xiao-xiao;XIAO Xiao-nian;LI Li;Sino-german Food Engineering Center,Nanchang University;Sino-german Joint Research Institution,Nanchang University;;Research on Drug Release Characteristics of Cinnamon Oil Microemulsion in Simulated Artificial Intestinal Juice[J];Natural Science Journal of Xiangtan University;2015-01
Chinese Journal Full-text Database 10 Hits
1 HuoHong FengLinXia(Dept.NorthChinaInstituteofTechnology,ShanxiTaiyuan030051);Research on Synthesis Technology of Cinnamaldehyde[J];Anhui Chemical Industry;2002-02
2 ZHANG Jian et al (Food College,Shihezi University,Shihezi,Xinjiang 832003);Study on the Purification of Crude Extract of Tannin from Grape Stalks by Macroporous Resin Adsorption[J];Journal of Anhui Agricultural Sciences;2008-36
3 LI Pin-ai et al (Luohe Medical College,Luohe,Henan 462002);Study on Antioxidative Capacity in Volatile Oil of Cinnamomum cassia[J];Journal of Anhui Agricultural Sciences;2010-24
4 DU Yun-ping et al(Institute of Chemical Industry of Forest Products,CAF;National Engineering Lab for Biomass Chemical Utilization;Key and Open Lab on Forest chemical Engineering,SFA;Key Lab of Biomass Energy and Material,Nanjing,Jiangsu 210042);Study on Preparation of Chestnut Shell Tannin by Polysulfone Membrane[J];Journal of Anhui Agricultural Sciences;2011-11
5 MENG Jiang-ping et al(School of Chemistry and Environmental Engineering,Chongqing University of Arts and Sciences,Chongqing 402160);Research and Application of Supercritical CO_2 Fluid Extraction in the Extraction of Active Components from Traditional Chinese Medicines[J];Journal of Anhui Agricultural Sciences;2011-22
6 CHEN Wei-wei,LI Jun,SONG Jue(School of Pharmacy,Anhui Medical University,Hefei,Anhui 230032,China);Study methods progress on drug intestinal absorption[J];Anhui Medical and Pharmaceutical Journal;2009-04
7 JIN Ge 1 ,ZHANG Ting 2 ,WANG Tao 3 ,YANG Li-ping 2 1.Department of Biochemistry,Medi cal College,Zhengzhou University,Zhengzhou 450052,P.R.China.2.Department of Biochemistry,Henan Traditional Chinese Medical Colle ge,Zhengzhou 450003,P.R.China.3.Departmen;Inhibition of α-Interferon and Cinnamic Acid on Pro liferation of Human Lung Cancer Cell[J];Chinese Journal of Cancer;2002-08
8 Zhai Bao- Jin1, Wu Feng1, Shao Ze- Yong1, Hu Kai2, Wang Zhi- Biao2 1.The Center for Tumor Therapy,The Second Affiliated Hospital,Chongqing University of Medical Science, Chongqing,400016, P.R.China 2.Institute of Ultrasound and Engineering in Medicine,Chongqing University of Medical Science, Chongqing,400010, P.R.China;Establishment of Human Multidrug- Resistant Hepatocellular Carcin oma Cell Line (HepG2/Adm) and Biological Characteristics Evaluation[J];Chinese Journal of Cancer;2004-04
9 Shuang Chen,1 Yan Xie,2 Chun-Hui Wang2 and Cheng-Wei Tang1,21. Division of Peptides Related with Human Disease, MOE Key Laboratory of Biotherapy of Human Disease, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, P. R. China 2. Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, P. R. China;Effects of octreotide on necrosis of hepatocellular carcinoma xenografts in nude mice[J];Chinese Journal of Cancer;2009-07
10 TIAN Yu-hong1,LI Ri-nan2,ZOU Ke-xing2,CHEN Zhi-yan2,JIANG Hong-lin2(1.Department of Biological and Chemical Engineering,Guangxi University of Technology,Liuzhou,Guangxi 545006;2.Technology Centre,China Tobacco Guangxi Industrial Corporation,Liuzhou,Guangxi 545005);Influence of Distillation Time on the Composition of Essential Oil from Cinnamomum cassia Presl and Its Tobacco Flavoring Effect[J];Northern Horticulture;2011-05
【Secondary References】
Chinese Journal Full-text Database 7 Hits
1 ;Impact Analysis of Bushenyisui Decoction on Poisonous Side Effect of Chemotherapy with Leukemia Patients[J];Hubei Journal of Traditional Chinese Medicine;2015-02
2 LI Yan;MIAO Mingsan;Henan University of Traditional Chinese Medicine;;Discussion on the Chemical,Pharmacology and Application Characteristics of Cinnamon[J];China Journal of Chinese Medicine;2015-09
3 CHEN Hui-yun;MA Li;LAI Fang;LI Wei-guang;LIU Jia-ling;LIU Xiong-min;School of Chemistry and Chemical Engineering,Guangxi University;;Study on extraction technology of tannin from Cinnamon[J];Science and Technology of Food Industry;2014-16
4 ZHOU Xiufang;WANG Yuewu;LI Xiaoxu;LIU Teng;Department of Pharmacy, the Affiliated Hospital of Inner Mongolia Medical University,Inner Monggol Autonomous Region;College of Pharmacy, Inner Mongolia Medical University,Inner Monggol Autonomous Region;Department of Pharmacy, Beijing Tiantan Hospital;;Study on the different extraction technology and inclusion technology of volatile oil of Anari Wuwei Powder[J];China Medical Herald;2013-35
5 Zhu Yuyao;Qian Hua;Zhang Qiyao;Huang Xiaode;Chen Bin;Zhao Botao;Nanjng Institute for Comprehensive Utilization of Wild Plants;;Chemical Components and Antimicrobial Activity of Essential Oil Extracted from Five Different Parts of Cinnamomum cassia[J];Chinese Wild Plant Resources;2014-06
6 DOU Hai-gang;LI Ting;HOU Xiao-dong;Biological Engineering Department,Zhoukou Vocational & Technical College;Guangdong Chaozhou Institute of Quality and Metrology Supervision and Inspection;;Study on Scavenging Free Radical and Antibacterial Ability of Cinnamon Bark Extract[J];China Condiment;2015-02
7 HE Xiao-ying;XU Dong-ying;LIAO Zheng-fu;CAO Guo-xuan;Research Management Office of Guangxi Academy of Sciences;School of Pharmaceutical and Chemical Engineering,Guangdong Pharmaceutical University;School of Materials and Energy,Guangdong University of Technology;;Research Progress of Extraction Methods for Natural Cinnamon Essential Oil[J];China Condiment;2015-03
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