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《Chinese Journal of Microecology》 2012-04
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The homogeneity of carbapenem-resistant Acinetobacter baumannii in ICU

LV Wan-fei,WANG Li,MAO Xiong-ying,MA Hong-ying,CHEN Qiao-qiao(Department of Laboratory,the Affiliated Hospital of Ningbo University,Ningbo 315020,China)  
Objective To investigate the homogeneity and molecular epidemiology of carbapenem-resistant Acinetobacter baumannii(CRAB) from ICU.Method 40 strains of CRAB isolates were collected from 2010.2-2011.5 in ICU of our hospital.Susceptibility was tested by Kirby-Bauer(K-B) method.The homology of the resistant isolates was examined by pulse-field gel electrophoresis(PFGE).Result The sensitivity rate to amikacin was the highest,reaching up to 100%,followed by minocycline(50%);All of the 40 isolates belonged to three PFGE pulsotypes(A,B,C).There were 22 Pulsotype A isolates(16 isolated during February to March in 2010 and 6 during January to February in 2011),16 Pulsotype B isolates(during May to June in 2011),and 2 pulsotype C isolates(1 of subtype C1,1 of subtype C2).Conclusion The emergence of CRAB in the Affiliated Hospital of Ningbo University is associated with the spread of Acinetobacter baumannii strains of clone A and B.
【CateGory Index】: R446.5
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