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《Chinese Journal of Microecology》 2012-04
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Drug resistance analysis of Escherichia coli causing surgical incision infection

FENG Lei1,MAO Guo-feng2(1.Operation room;2.Department of Clinical Laboratory,Shaoxing People′s Hospital,Shaoxing 31200,China)  
Objective To explore the detection ratio and drug resistance of Escherichia coli in surgical incision infection for clinical rational medication.Method The drug resistance of Escherichia coli in surgical incision infection from June 2009 to October 2010 was analyzed and the isolated strains producing extended spectrum β-lactamase(ESBLs) were identified using Phenotypic Confirmatory Test.Result The detection rate of ESBLs producing Escherichia coli strains were 42.14% among the 140 isolated strains,which had high drug resistance ratio to the first to fourth-generation of cephalosporin,penbritin,Quinolone and aminoglycosides.Non ESBLs-producing E.coli had a high sensitivity to most of the antibiotics except penicillins.The drug resistance ratio of ESBLs producing E.coli was higher than that of non ESBLs producing E.coli significantly(P0.05).Conclusion The ESBLs producing E.coli has a high detection ratio in surgical incision with a high drug resistance.It is necessary to further monitor and control the production and spread of the drug resistant bacterium.
【CateGory Index】: R446.5
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