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《Chinese Journal of Microecology》 2014-01
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Lacidophilin Vaginal Capsules combined with Estriol Cream for treatment of senile vaginitis: an efficacy observation

LIU Jiao;Department of Gynaecology and Obstetrics, Qingtian Traditional Chinese Medicine Hospital;  
Objective To observe the curative effect of Lacidophilin Vaginal Capsules combined with Estriol Cream on senile vaginitis( SV). Methods 90 patients with SV were selected and divided into observation group and control group at random. The patients in observation group were given 0. 5 mg of Estriol Cream topically once daily at night,and Lacidophilin Vaginal Capsules two capsules once daily at night for 2 weeks. The patients in control group were only given Estriol Cream with the same dose,usage and period of treatment as those of observation group. The clinical curative effect and safety profile,as well as the reoccurrence rates in the two groups were observed. Results After 2 weeks' treatment,the total clinical efficacy rate in observation group was 93. 33%, which was significantly higher than that in control group( 77. 78%)( χ2= 4. 41,P 0. 05). There were 3 cases of adverse reactions in observation group and 1 case in control group; the difference was not significant( χ2= 0. 26, P 0. 05) and the symptoms were mild. After 6 months' following-up,8( 19. 05%) and 14( 40. 00%) cases of reoccurrence were seen in observation group and control group,respectively,and the difference was significant( χ2= 4. 11,P 0. 05). Conclusion Lacidophilin Vaginal Capsules combined with Estriol Cream has reliable curative effect on SV,which can obviously improve the clinical symptoms and reduce the reoccurrence rate.
【CateGory Index】: R711.31
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