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《Chinese Journal of Microecology》 2017-08
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Analysis of hepatitis B surface antigen and hepatitis B surface antibody positive in pregnant couple

LI Saiqin;Xiangshan Province Family Planning and Technical Guidance Station;  
Objective To analyze and explore the results of hepatitis B surface antigen(HBsAg)and hepatitis B surface antibody(HBsAb)test,and study its effect and evaluation on clinical pre-pregnancy examination.Methods 4,880 cases pregnant couple who received pre-pregnancy examination in our hospital from 2015 to 2017 were selected as the research subjects,and divided into two groups randomly,with 2,440 cases in each group.Both two groups were tested for HBsAg and HbsAb during pre-pregnancy examination.The preganat couple who received HBsAg and HbsAb test in our hospital from March 2015 to February 2016 were included into the group A,and the pregnant couple who received HBsAg and HbsAb test in our hospital from March 2016 to February 2017 were included into the group B.The positive result of HBsAg and HbsAb test were compared between two groups.Results The positive rates of HbsAg(6.43%)and HbsAb(62.99%)in the group B were significantly higher than the positive rates of HbsAg(4.63%)and HbsAb(58.44%)in the group A,and the differences were statistically significant(P0.05).The positive rate of HbsAg in male of the group B(59.87%)was significantly higher than that in female of the group B(40.13%),the positive rate of HbsAb in male(46.52%)was lower than that in female(53.48%);The positive rate of HbsAg in male of the group A(60.18%)was significantly higher than that in female of the group A(39.82%),the positive rate of HbsAb in male(47.41%)was lower than that in female(52.59%),and the difference were statistically significant(P0.05).The positive rates of HbsAg of patients with the education of high school and above in group B(38.85%)was significantly lower than the positive rates of HbsAg of patients with edication of lower than high school in group B(61.95%),the positive rates of HbsAb of patients with the education of high school and above(53.15%)was higher than the positive rates of HbsAg of patients with edication of lower than high school(46.84%);The positive rates of HbsAg of patients with the education of high school and above in group A(38.05%)was significantly lower than the positive rates of HbsAg of patients with edication of lower than high school in group A(61.15%),the positive rates of HbsAb of patients with the education of high school and above(51.75%)was higher than the positive rates of HbsAb of patients with edication of lower than high school(48.25%),and the differences were statistically significant(P0.05).Conclusion At present,the infection of hepatitis B in our city is still increasing.The enhancement of HBsAg and HbsAb test in pregnant couples who received pre-pregnancy examination is helpful for the early diagnosis,intervention and treatment,reduce the spread of hepatitis B,and can effectively reduce the incidence of neonatal hepatitis B,promote better prenatal and postnatal care,and improve the overall quality of the birth population.
【CateGory Index】: R512.62
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