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《CHINESE JOURNAL OF MICROECOLOGY》 1998-01
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PRELIMINARY RESEARCH OF LACTOBACILLUS ACIDOPHILUS ON ACTIVATION AND CYTOTOXICITY OF MURINE PERITONEAL MACROPHAGE

Ge Fengxia et al. Dalian No.3 People Hospital,Dalian 116037  
Activation and cytotoxicity of Lactobacillus Acidophilus (LA) on murine peritoneal macrophage was studied. The results showed that this LA could activate murine peritoneal macrophage. After injected LA, the cytotoxicity of peritoneal macrophage in vitro and in vivo enhanced. the contents of acidic phosphophate enzymes and nonspecific esterase increased, LA also enhanced secretion of TNF-α in supernatant of M. The electron microscope showed:the cellular size increased, number of pseudopods、lysosomes and mitochondrion increased. It was suggested that LA vaccine can enhance the activation and cytotoxicity of M.
【CateGory Index】: R37-33,
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