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《Chinese Pharmaceutical Journal》 2012-13
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Study on Chemical Constituents of Alocasia macrorrhiza(L.) Schott

ZHU Ling-hua,HUANG Xiao-sheng,YE Wen-cai,ZHOU Guang-xiong(Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Chinese Materia Medica and New Drugs Research;Institute of Traditional Chinese Medicine & Natural Products,College of Pharmacy,Jinan University,Guangzhou,510632,China)  
OBJECTIVE To study the chemical constituents of Alocasia macrorrhiza(L.) Schott.METHODS Chemical constituents were extracted by organic solvents,isolated and purified by chromatographic techniques with silica gel,polyamide,ODS,Sephadex LH-20,semi-preparative HPLC and recrystallization.Their structures were identified on the basis of physicochemical properties and spectral data analyses of MS and NMR,et al.RESULTS Nine compounds were isolated from its rhizoma and identified as glycosmisic acid(1),N-trans-feruloyltyramine(2),grossamide(3),protocatechuic acid(4),borneol acetate(5),vanillic acid(6),methyl 4-hydroxybenzoate(7),β-daucosterol(8),and β-sitosterol(9).CONCLUSION Compounds 1-9 were isolated from Alocasia macrorrhiza for the first time.
【Fund】: 广东省自然科学基金团队项目(8351063201000003);; 暨南大学211工程项目
【CateGory Index】: R284.2
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