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《Chinese Journal of Clinical Oncology and Rehabilitation》 2004-06
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Clinical study on mediastinal lymph node metastatic rate of en bloc esophagectomy

PANG Zuo-liang,SUN Wei,ZHANG Guo-qing,et al (Department of Tharacic Surgery,Affiliated Tumor Hospital of Xinjiang Medical University,Urumqi,830011,China)  
Objective To study the mediastinal lymph node metastasis rate(LMR) of thoracic esophageal carcinoma treated with removal of total thoracic esophageal tube and extensive resection of regional lymph nodes and soft tissue.Methods Eighty-six patients with thoracic esophageal squamous-cell carcinoma and mediastinal lymph node metastasis who underwent en bloc esophagectomy were analysed retrospectively.Results 1806 lymph nodes were dissected with an average of 18±4.6(15-30)lymph nodes in each case. 253 lymph nodes had metastasis and the mediastinal LMR was 14.0%(253/1806). LMR was statistically different between middle and upper,lower mediastinum(P0.01).The site of thoracic esophageal carcinoma was correlated to upper,middle,and lower mediastinal LMR(P0.01).Statistical correlation was found between postoperative T-staging and mediastinal LMR(P0.01).There was no statistical correlation between the length of lesion and LMR(P=0.203) and between the site of thoracic esophageal carcinoma and “jumping” mediastinal lymph node metastasis(P=0.933).Conclusions LMR of thoracic esophageal carcinoma showed bidirectional metastasis,different regional LMR of mediastinum correlated to the site of lesion and postoperative T-staging.The regional mediastinal lymphnode draining thoracic esophageal carcinoma should be dissected strictly.
【CateGory Index】: R735.1
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【Co-references】
Chinese Journal Full-text Database 10 Hits
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