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《Chinese Journal of Clinical Oncology and Rehabilitation》 2004-06
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Clinical application of measuring the serum laminin in patients with colorectal cancer

YIN Dong,WANG Hai-jiang,GUI Xia,et al (Affiliated Tumor Hospital, Xinjiang Medical University,Urümqi 830011,China)  
Objective To investigate the changes of serum contents of laminin (LN) in preoperative and postoperative patients with colorectal cancer and its value in diagnosis and prognosis of the cancer,and to evaluate the clinical significance of serum LN in neoplastic relapse and metastasis as compared with CEA and CA 242. Method The contents of LN, CEA and CA 242 in serum were measured by radioimmunoassay in patients with colorectal cancer.Results In 44 colorectal cancer patients,the specificity,sensitivity and accuracy of serum LN in diagnosis of the cancer were 84.1%,92.7% and 89.3% respectively.The contents of serum LN in all cancer groups of different Dukes stages were significantly higher than those in control group and benign disease group (P0.05). There was no difference between control group and benign disease group (P0.05). The contents of LN in Dukes C and D were higher than those in Dukes A and B(P0.05).The content of LN in postoperative group was lower than that in preoperative group (P0.05).In all patients with colorectal cancer, the positive rate of LN was higher than those of CEA and CA 242(P0.05).Conclusion Serum LN is helpful to diagnosis, judgment of prognosis and instructing clinical therapy of colorectal cancer.
【CateGory Index】: R735.34
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Chinese Journal Full-text Database 2 Hits
1 Feng Shu, Song Jindan (Department of Cell Biology, School of Basic Medical Sciences, China Medical University, Shenyang, 110001);Expression of Endoplasmic Reticulum Synthesized Laminin in Colorectal Carcinomas[J];JOURNAL OF CHINA MEDICAL UNIVERSITY;1997-04
2 Bao Xiusheng Bao Jiangping The central Hospital of Jiang Han oil Field,Qianjiang 433124;The dinical use value of the serum laminin protein[J];CANCER RESEARCH ON PREVENTION AND TREATMENT;1999-01
Chinese Journal Full-text Database 2 Hits
1 Zhao Junli, Wang Shuyu, Zheng Yiling, et al. Department of Gynecology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029;The Expression and Significance of Laminin of Three Different Endometrium[J];ACTA ACADEMIAE MEDICINAE NANJING;2000-03
2 YIN Dong,WANG Hai-jiang,GUI Xia,et al. Affiliated Tumor Hospital,Xinjiang Medical University,Xinjiang,830011;Dynamic Detection of the Serum Laminin in Preoperative and Postoperative Patients With Colorectal Cancer and its Clinical Significance[J];The Practical Journal of Cancer;2004-02
Chinese Journal Full-text Database 10 Hits
1 ZHANG Xin-min,WANG Jiao-chen. Department of Pathology, The Second Xiangya Hospital, Central South University,Changsha 410011,China;Expression of Collagenase Ⅳ and Collagen Type Ⅳ in Papillary Thyroid Carcinoma[J];Journal of Chinese Physician;2004-05
2 LI Ying-jia 1 ,WANGDong 2 ,ZHOUYa 3 Departmentsof Ultrasonography 1 andRespiratoryDiseases 3 ,NanfangHospital,FirstMilitaryMedicalUniversity,Guangzhou510515,China;2 Departmentof Pathology,DapingHospital,ThirdMilitaryMedic;Observation of the microstructure and ultrastructure of microvessels induced by OS -732cell line[J];Journal of First Military Medical University;2002-02
3 YANG Fang, HE Yuan-li Department of Obstetrics and Gynecology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China;Recombinant human endostatin induces apoptosis of human umbilical venous endothelial cells[J];Journal of Southern Medical University;2006-07
4 LI Ronghua,ZHANG Chen,WANG Bangmao,et al.Department of Oncology,The Third Hospital of Hebei Medical University,Hebei,Shijiazhuang 050051;A study on the change of the serum levels of soluble sCD44v6 and the expression of CD44v6 in the tissues of gastric tumor[J];Hebei Medical Journal;2006-05
5 Liu Gang, Li Jinrong, Li Zubing\;College of Stomatology, Hubei Medical University\;Yan Junfeng\;The Police Hospital of Hubei;Measurement of Content of Collagen Type Ⅳ and Laminin in Tissue of Oral Squamous Cell Carcinoma and Its Clinical Significance[J];WEST CHINA JOURNAL FOF STOMATOLOGY;2000-02
6 Deng yuehua, Liu Gongchuan,Liu Yi.The First Affiliated Hospital of Anhui Medical University,Hefei 230022;Expression of seum laminin and collagen type Ⅳ in patient with gastric cancer and clinical implication.[J];Central China Medical Journal;2002-01
7 ZHANG Liang-yun ,PENG Jun,SONG Yin,et al (Institute of Oncology, Nanhua University, Hengyang,Hunan 421001,China);Effect of Tween Compounds on Human Gastric Cancer Cell Line MGC803 in Vitro[J];Journal of Nanhua University(Medical Edition);2004-01
8 WANG Jian-huo, ChEN Zi-fu, CHEN Wen-bang,SHI Zuo-lin, (Department of Urology, 476th Hospital of PLA,Fuzhou 350002 Fujian Province, China);Signfficance of collagen TV expression in bladder cancer[J];Journal of Modern Urology;2003-01
9 ZHOU Hong~1, SUN Hai~2, ZHONG Yi~3(1. Dept. of Emergency and Incident, Zhuhai Branch Hospital of Second Affiliated Hospital, Guangzhou University of TCM, Guangzhou 519015, China; 2. Doctoral Graduate, First Military Medical University, Guangzhou, 510515, China; 3. Doctoral Graduate, Guangzhou University of TCM, Guangzhou 510405, China);In-Vitro Inhibitory Effect of Oleum Curcumae Aromaticae on Leukemia Cell Strain[J];Journal of Guangzhou University of Traditional Chinese Medicine;2004-02
10 Zheng Guangjuan (Shandong University of Traditional Chinese Medicine,Jinan 250014);Baizhu's Effect of Suppressing Tumors on S_(180) sarcoma and the Effect of Baizhu on Metastasis-associated Gene bcl-2[J];Journal of Biomedical Engineering Research;2003-03
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