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《Chinese Journal of Clinical Oncology and Rehabilitation》 2004-06
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Clinical efficacy of bleomycin plus cisplatin in treatment of malignant effusion

WANG Dong-hai (Songzi People's Hospital of Hubei Province,Songzi 434200, China)  
Objective To evaluate the antitumor efficacy of bleomycin(BLM) plus cisplatin in treament of malignant pleural effusion.Methods Thirty-six patients with malignant pleural effusion were randomly divided into two groups.Twenty cases were treated with BLM plus DDP(treatment group) and another sixteen cases were treated with MMC plus DDP(control group).Results The total effective rate of treatment group was 95.0%,while was 81.3% in control group(P0.05). The Karnofsky of the treatment group was higher than that of the control group. The main side effects were fever.Conclusion BLM can effectively control the malignant pleural effusion and improve the life quality of patients,and the side effect is less.So it is the first choice of treatment for malignant pleural effusion.
【CateGory Index】: R730.5
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