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《Chinese Journal of Clinical Oncology and Rehabilitation》 2012-01
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Result and prognostic analysis of ~(18)FDG PET/CT positioning three-dimensional conformal radiotherapy for gastric cardiac carcinoma

REN Bao-zhi,ZHOU Yu-xia,ZHONG Li-song,et al(Department of Oncology,Deyang First Hospital,Deyang 618000,China)  
Objective To analyse the result of 18FDG PET/CT positioning three-dimensional conformal radiotherapy(3DCRT) for gastric cardiac carcinoma.Methods 46 cases of gastric cardiac carcinoma patients were randomly divided into 18FDG PET/CT positioning 3DCRT group(PET/CT group)and the general CT dimensional conformal radiotherapy group(normal CT group).The location of PET/CT group′s cases was determined by PET/CT and the date was transmitted to the treatment planning system(TPS),the PET image and CT image were fused together;Target volume and critical organs were determined and the treatment plan was worked out by the fused image,then conventional fraction′s 3DCRT(40 Gy or so) was followed to a total dose of radiotherapy 60 Gy~70 Gy by reduced radiation field;The location of normal CT group′s cases was determined by normal CT and the date was transmitted to the TPS and were treated by 3DCRT to the same dose.Results The average GTV′s and PTV′s volume、left and right lung′s V20、left and right kidney′s V20、stomach、heart、esophagusspinal and cord′s irradiated volume of the PET/CT group were smaller than that of the normal CT group(all P0.05);The local control rates and 1,2,3-year survival rates of the PET/CT group were higher than that of the normal CT group(all P0.01);The early trachea、esophagus and lung′s 1,2-grade side effects of the PET/CT group were lower than that of normal CT group(P0.05);Multivariate analysis showed youth and that lesion length ≤5cm and early T stage lesions were better than that of others(all P0.01).Conclusion PET/CT positioning 3DCRT can optimize the radiation treatment planning of gastric cardiac carcinoma,reduce the early radiation side-effects of normal tissue,lesion length ≤5cm and early T stage lesions were better than that of others.
【CateGory Index】: R735.1
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