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《Chinese Journal of Clinical Oncology and Rehabilitation》 2012-06
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Analysis of prognostic factors affecting radiofrequency ablation for primary hepatic carcinoma

KONG Yi,LI Ke(Department of hepatopancreatoblliary of Hunan provincial tumor hospital,Changsha 410205,China)  
Objective To investigate the prognostic factors affecting outcome in radiofrequency ablation for primary hepatic carcinoma,and to select the individualized treatment plan for patients and estimate prognosis.Methods Retrospectively analyzed 134 patients with primary hepatic carcinoma treated by RFA,with the survival time and survival outcomes as the dependent variable,to analyze 11 possible prognostic factors affecting outcome.Kaplan-Meier model and Log-rank test were used in univariate analysis and COX proportional hazards model was used in multivariate analysis.Results Three months after treatment,follow up survey for patients was made to June 2012,with the rate of 95.5%.In results of univariate analysis,6 factors were statistically significant:Child-Pugh grade,tumor type,portal hypertension,AFP value,treatment purpose and pre-optional TACE treatment.Results of COX model multivariate analysis revealed that 4 factors were associated with survival rate:Child-Pugh grade,portal hypertension,treatment purpose and pre-optional TACE treatment.Conclusions There are 4 factors affecting the prognosis of patients with primary hepatic carcinoma:Child-Pugh grade,portal hypertension,treatment purpose and pre-optional TACE treatment,which are helpful for guiding RFA treatment for patients with primary hepatic carcinoma.
【CateGory Index】: R735.7
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