Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Clinical Oncology and Rehabilitation》 2018-09
Add to Favorite Get Latest Update

Small intestinal bacterial overgrowth and clinicopathological features in patients with gastrointestinal stromal tumors

WANG Ning;YU Xing-hua;XU Lin;Department of Gastroenterology,Qingdao Municipal Hospital Affiliated to Qingdao University;  
Objective To investigate the intestinal bacterial overgrowth( SIBO) and the clinicopathological features in patients with gastrointestinal stromal tumors( GIST) and its clinicopathological features. Methods The clinical data of 52 patients with GIST were collected at Qingdao Municipal Hospital from June 2015 to June 2017. Another 30 individuals who had physical examination were selected ast the same as the control group. Glucose hydrogen breath test( GHBT) was used to detect preoperative SIBO in patients with GIST and the healthy controls. Histopathological examination of tumor specimens and grading of postoperative risk were performed. Results The positive rate of SIBO in patients with GIST( 53. 8%)was significantly higher than that in the healthy subjects( 16. 7%)( P 0. 05). GIST occurred in the stomach in 35 patients,occurred in small intestine in 12 patients and in duodenum in 5 patients. The classification of the risk degree of the tumors: very low risk in 10 patients( low risk in 15 patients,moderate risk in 7 patients and high risk in 20 patients. The positive expression rates of immunohistochemistry CD117,CD34,DOG-1,SMA,S-100 and Ki-67 were 96. 2%,65. 4%,90. 4%,7. 7%,3. 9% and 34. 6%. Conclusion Gastrointestinal stromal tumors are more likely to occur in SIBO than healthy people. The clinical manifestations of gastrointestinal stromal tumors are lack of specificity. The value of CD117,CD34 and DOG-1 were high in the diagnosis of GIST.
【Fund】: 青岛市科技局立项课题(13-1-3-14-nsh);; 青岛市医疗卫生优秀人才培养项目
【CateGory Index】: R735
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved