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《Chinese Journal of Clinical Oncology and Rehabilitation》 2018-09
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Parallel overlapping anastomosis combined with complete mesocolic excision in the treatment of laparoscopic surgery for colon cancer and the effects on SOFA

LYU Qiang;ZHONG Ming;WANG Hai-chuan;Department of General Surgery,Shanghai Pudong New Area Gongli Hospital;Department of Gastrointestinal Surgery,Renji Hospital Affiliated to Shanghai Jiaotong University;  
Objective To explore parallel overlapping anastomosis combined with complete mesocolic excision( CME) in the treatment of laparoscopic colon cancer and the effects on sepsis-related organ failure assessment( SOFA). Methods A total of 90 patients undergoing resection for colon cancer at Shanghai Pudong New Area Gongli Hospital between November 2016 and November 2017 were enrolled and retrospectively analyzed. They were divided into an observation group and a control group with 45 patients in each group. The observation group was treated with radical resection for colon on the basis of CME and the control group only underwent traditional laparoscopic surgery for colon cancer.,The intraoperative parameters,postoperative clinical efficacy,postoperative parameters,SOFA score,adverse reactions,and 6-month recurrence rate were compared between the two groups. Results The efficacy rate of treatment was significantly higher in the observation group than in the control group( P 0. 05). The operation time and intraoperative blood loss were significantly lower in the observation group than in the control group,and the number of lymph node removed was significantly higher in the observation group than in the control group( all P 0. 05). The anus exhaust time and length of hospital stay were significantly lower in the observation group than in the control group( all P 0. 05). There was no significant difference in SOFA scores between the two groups at 1 d after the surgery( P 0. 05),and SOFA scores were significantly lower in the observation group than in the control group at 3 d after the surgery( P 0. 05). There was no significant difference in the incidence of adverse reactions between the two groups( P 0. 05). The 6-month recurrence rate was significantly lower in the observation group than in the control group( P 0. 05). Conclusion Parallel overlapping anastomosis combined with CME can better remove the lymph nodes,reduce the recurrence rate,reduce the damage and promote postoperative recovery in patients with colon cancer. At the same time,it also reduces SOFA score and improves prognosis.
【CateGory Index】: R735.35
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