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《Chinese Journal of Clinical Oncology and Rehabilitation》 2018-09
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Effect of psychological nursing on chemotherapy-induced nausea and vomiting in patients with advanced primary liver cancer

YANG Jian-fen;SHEN Yong-qi;KONG Xiang-ying;CHEN Chao-ting;SI Tao;WANG Zhi-xiang;XIE Hua-dong;Department of Oncology,Guangxi Medical University Affiliated Liutie Central Hospital;Department of Oncology,Third Affiliated Hospital of Guiyang College of Traditional Chinese Medicine;The Second Department of Chemotherapy,The Second Affiliated Hospital of Guangxi University of Science And Technology;The Second Department of Oncology,The Third Affiliated Hospital of Guangxi University of Traditional Chinese Medicine;The First Department of Oncology,The Third Affiliated Hospital of Guangxi University Of Traditional Chinese Medicine;Department of Oncology,Liuzhou Rongshui County People's Hospital;  
Objective To evaluate the effect of psychological nursing on chemotherapy-induced nausea and vomiting( CINV) in patients with advanced primary liver cancer( PLC). Methods One hundred and nine patients with advanced PLC admitted to 6 cancer center hospitals from July 2013 to March2017 were selected and divided into an observation group( 57 patients) and a control group( 52 patients).Both groups received chemotherapy and conventional care. Concurrently,the observation group was also given psychological nursing but the control group was not. The incidence and strength of CINV duiring each course were investigated in this study. Results Two hundred and ninety-six chemotherapy cycles were carried out in the observation group and 243 chemotherapy cycles were completed in the control group. The incidence of chemotherapy-induced nausea and vomiting was 43. 6% and 35. 5%,respectively in the two groups and 53. 1% and 46. 9%,respectively in the control group( all P 0. 05). No grade Ⅳ ~ Ⅴchemotherapy associated vomiting occurred in the two groups and there was no difference in grade Ⅰ CINV between the two groups( P 0. 05). The incidence of grade Ⅱ and Ⅲ chemotherapy associated nausea was 14. 2% and10. 1%,respectively for the observation group and 21. 0% and 16. 9%,respectively for the control group( all P 0. 05). The incidence of grade Ⅱ and Ⅲ chemotherapy associated vomiting was 12. 5% and9. 5%,respectively for the observation group and 18. 9% and 15. 2%,respectively for the control group( all P 0. 05). Conclusion Psychological nursing can reduce the incidence rate and decrease severity degree of CINV in patients with advanced primary liver cancer.
【Fund】: 广西卫计委科研项目(Z2014408);; 柳州市科技攻关项目(2014J030424)
【CateGory Index】: R473.73
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