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《Chinexe Journal of Pediatrics》 1995-01
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A SURVEY ON HUMAN CYTOMEGAL-OVIRUS INFECTION IN CHILDREN ANDBLOOD-DONORS IN CHANGCHUN

HOu Zhi-fu; Wang Weizhong; Mo Xiufen et of. (ThirdTearhing Hospital, Norman Bethune Universityof Medical Scicmes, Changchun 130021)  
uman cytomegalovirus (HCMV) infection wasstudied in 129 blood donors and children of Changchunarea by using nucleic acid hybridization method. The re-sults showed that HCMV carrier rate was 17. 1% inblcod-donors and 19. 8% in children. In children, thedifferences in HCMV-DNA positive rate in blood werenot statistically significant among different age groups,but it was higher in girls than in boys older than 10years. The rate of HCMV shedding in urine was15. 6% , significantly higher in 1~5 years old childrenthan the others. The risk of post-transfusion HCMV in-fection in children was 5. 3 times of that of the controlgroup. The results suggest that blcod transfusion is animportant route of transmission of HCMV infection.Children under 5-years of age should be the main popu-lation monitored for HCMV infection.
【CateGory Index】: R511.01
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