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Cardioprotective effect of angina within 48 hours before acute myocardial infarction in the aged

Cheng Youqin;Cui Jijun.(The General Hospital of Beijing Military 100700)  
Objective(1) To determine whether angina prior to acute myocardial infarction(AMI) affects the clinical course of first AMI in the aged.(2) To evaluate the possible effect of ischemia preconditioning as a result of angina on the prognosis of AMI.Methods Two hundred and sixty-three aged(≥60) cases of first AMI were investigated to examine the in-hospital course and short-term prognosis. Patients were divided into 2 groups:AP group,angina occurred winthin 48 hours before AMI onset;control group,no angina occurred.The basic clinical characteristics of the 2 groups were similar.Results The incidences of heart failure and serious arrhythmia during hospitalization were lower in the AP than those in the control group.(32/124,25.8% vs 56/139,40.3%;32/124,25.8% vs 61/139,43.9%;respectively).The peak value of CPK and fatality rate during hospitalization were also lower in the AP than those in the control group(264±330 vs 314±326U/L,8/124,6.8% vs 21/139,16.5%;respectively).Conclusion The aged patients with angina pectoris within 48 hours before AMI onset had better in-hospital course and short-term prognosis.These favorable effects of angina were related to the ischemia preconditioning.
【CateGory Index】: R542.220.5
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