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《CHINESE JOURNAL OF PHARMACEUTICALS》 1998-08
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SYNTHESIS OF DICLOFENAC SODIUM BY REARRANGEMENT Ⅱ.

CHEN FenEr*,DENG Yan,HU YeLi,WAN JiangLing(Centre of Synthetic Drugs,Wuhan Institute of Chemical Technology,Wuhan 430074)  
N(2,6Dichlorophenyl) aniline prepared from aniline by chloroacetylation,etherification and rearrangement in onepot procedure was subjected to chloroacetylation,cyclization and hydrolysis to afford diclofenac sodium in 64% overall yield based on aniline.
【CateGory Index】: TQ460.6
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