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Clinical analysis of non-functioning pancreatic Islet Cell tumors—A report of 6 cases and literature review

HU Shi-qi LIU Zhen-bang ZHANG Xin-hua. Department of Gastrointestinal Surgery, The First Municipal People's Hospital of Guangzhou, Guangzhou 510180,China  
Objective To study the clinical diagnosis and treatment of nonfunctioning pancreatic islet cell tumors. Method Six patients with nonfunctioning pancreatic islet cell tumors were analyzed retrospectively. Results All of the 6 cases were treated with surgery after radiological tests. 5 cases turned out to be malignant tumors, and 3 were still alive with post-operational adjuvant chemotherapy. 2 died from tumor metastasis, and 1 case with benign tumor was out of contact. Conclusion Radiological and endocrinological examinations of pancreas are the main approaches for diagnosis of non functional pancreatic islet cell tumors. Patients often come with abdominal mass or metastases in the end stage, and the tumors are difficult to be detected in the early or middle stage for lacking specific clinical manifestation. Surgical resection is the treatment of choice. Post-operational adjuvant chemotherapy may be beneficial.
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