Pure red cell anemia caused by Azathioprine in renal transplant recipients
Xue Wu-jun; Chen Yong; Wang Wen-kai, et al. (First Affiliated Hospital, Xi'an Medical University, Xi'an 710061)
renal transplant recipients occured pure red cell anemia caused by Azathioprine (Aza). 7 of them occuwed pure red cell anemia in 2-6 weeks after taking Aza, and 6 by increasing the dosage of Aza rapidly. 11 of 13 patients were cured after stoping the use of Aza, but 2 of them developed bone marrow exhaustion and died of septicemia because of the continuing use of Aza. This study suggested that the pure red cell anemia may be cured after stoping the use of Aza. By taking CsA and avoiding rapid increase of Aza dosage might prevent the pure red cell anemia caused by Aza in renal transplant recipients.