The study on the autologous bone marrow transplantation purified in vitro with monoclonal antibody conjugated with immunotoxin
Yang Ke; Teng Ai-ping; Mao Bing-zhi; et al. (Beijing General Hospital of PLA, Beijing 100700)
ABMTs on 4 cases of common-ALL in remission were studied. The bone marrow was purified in vitro by complement mediated cytotoxicity. Three of them remained in complete remission after 42, 35, and 12 months respectively, and one relapsed after 4 month remission. The bone marrow of other 2 cases of Null-ALL and one case of common-ALL was purified in vitro by immunotoxin after their complete remission, and then they were treated by ABMT. Two of them remained in complete remission after 14 and 6 months respectively and one, after 5 months of remission, died of fulminant hepatitis.