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STUDY ON THE ROLE OF MoAb-HIP_2 lN GRANULOCYTE-MACROPHAGE PROGENlTORS AND ACUTE MYELOlDLEUKEMlA PROGENlTORS lN VlTRO

Shi Hong;Yan Wenwei;Han Junjing;et al (Institute of Hematology,CAMS,Tianjin,300020)  
cAb HIP_2 had been shown to stimulate colony for-mation of hematopoietic progenitors in vitro.Our resultsindicated that HIP_2 significantly stimulated granulocyte-macrophage progenitors colony formation in normal indi-viduals;acute myeloid leukemia(AML)patients at di-agnosis and in complete remission,but rarely stimulatedthe growth of AML progenitors.The data implied thatHIP_2 could be used to accelerate the recovery ofhematopoiesis during myelogenic aplasia afterchemotherapy and bone marrow transplantation.
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