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Study on the clinical and biological characteristics of 20 cases of chronic lymphoid leukemias

Sheng Ruilan,Zhu Guanrong,Xia Wei,et al.First Affiliated Hospital of Nanjing Medical University, Nanjing 210029  
Objective:To further define the chronic lymphoid leukemia (CLL).Methods: Tweenty cases of CLL classified after the FAB proposals(1989) were retrospectively analyzed.Results:Based on the clinical features,cell/tissue morphology,immunophenotype, IgH and TCR γ gene rearrangement serum or urine immunoglobulin levels, 16 cases of B lymphoid leukemia(12 of CLL, 1 of PLL ,2 of leukemia/lymphoma, and 1 of WM) as well as 4 cases of T lymphoid leukemia(2 of leukemia/lymphoma,1 of T LGLL ,and 1 of NK LGLL) were identified.The diagnostic criteria,cell morphology,biological characteristics and prognosis for CLL were discussed.Conclusion:T leukemia/lymphoma should be incorporated in the classification of CLL.
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