Famihal aggregation and HLA typing of pedigrees inIDDM
Wang Heng; Xiang Hongding; Sun Qi; et al.(Peking Union Medical Coilege Hospital, Beijing100730)
n 280 patients with IDDM, the positive familyhistory of diabetes was 26.8% of IDDM probands.The prevalence of diabetes in relatives was 68% in firstdegree relatives, 28% in second degree relatives, and4% in third degree relatives. HLA typing of 87 mem-bers in 13 pedigrees with IDDM was perfornied. Thesedata support the hypothesis that IDDM is amultigenic hereditary disorder.
【CateGory Index】： R587.1