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Clinic value of oxygenation index and standing compliance during treating acute lung injury with mechanical ventilation

LIU Chang-wen,QING Zhong-he,WANG Hai-yan,et al.Department Of ICU Afficitated Hospital Of Bengbu Medical College,Bengbu 233004,China [  
Objective To explore the clinic value of oxygenation index(PO 2/FiO 2) and standing compliance (Cst) by placing 14 patient of acute lung injury (AI) on low tidal volume with positive end -expiratory pressure (PEEP) and mirroring PO 2/FiO 2 and Cst .Methods Patient were optimally ventilated an A/C(V T8 ml/kg f 16/min flow 34L/min),gradually patients were on A/C+PEEP(5、10、15、20 cmH 20)for 30 min each .The FiO 2 was kept constant on four modes .Hemodynamics and oxygen metabolism parameters were obtained by using Swan-Ganz cather Results The PaO 2/FiO 2 progressive increase observed going from PEEP 5 to 20 cmH 2O. Cst was kept in 33 6±8 3 ml/cmH 2O(PEEP 10~15 cmH 2O).The Cst and DO 2 were down gradually (PEEP15cmH 2O). The peak inspiratory pressure (PIP) was increased ( P 0 05).Conclusion Mirroring PaO 2/FiO 2 and Cst was beneficial to choose the best PEEP and obtain the largest DO 2 during ALI with mechanical ventilation [
【Fund】: 安徽省教委科研中标课题!编号 :98JL170
【CateGory Index】: R443.6;R655.3
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