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《CHINESE JOURNAL OF CRITICAL CARE MEDICINE》 2000-01
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The relationship between nm23-H_1 gene expression and lymph node metastasis of the esophageal squamous cell carcinoma

ZHANG Lin-you,WEI Guan-chun,LIU Da-zhong,et al.The Second Affiliated Hospital,Harbin Medical University, Harbin Heilongjiang 150086, China [  
Objective To understand the relationship between the expression of nm23-H 1 gene and lymph node metastasis in the tissue of esophageal squamous cell carcinoma(ESCC).Method The expression of nm23-H 1 protein was examined in 26 ESCC without lymph node metastasis and 28 with lymph node metastasis using immunohistochimical S-P method Results Fourteen of 26 ESCC without lymph node metastasis and 14 of 23 ESCC with lymph node metastasis were positive for nm23-H 1 staining while the nm23-H 1 protein average positive rates were 39.6% and in ESCC without lymph node metastasis and 17.2% in ESCC with lymph node metastasis respectively.Conclusion The expression was not correlated with lymph node metastasis,but reduced expression of nm23-H 1 gene was associated with lymph node metastasis. [
【CateGory Index】: R735.1;R73-37
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【Citations】
Chinese Journal Full-text Database 2 Hits
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【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 JIA Shao-chang,ZHANG Ying,WANG Yao-hua,ZHANG Wei-bing.81 Hospital of PLA,Nanjing 210002,China;Influencing factors relative to lymphatic metastasis of rectal carcinoma[J];临床肿瘤学杂志;2008-06
2 Yin Z hitao *,Sun Jiyuan,Wu Wei,et al.\ \ *Department of Tumor,First Affiliated Ho spital, China Medical University,Shenyang 110001,China;Influencing factors for lymphatic metastasis of rectal carcinoma[J];中国实用外科杂志;2004-03
3 ZHANG Lin-you,WEI Guan-chun,LIU Da-zhong,et al.The Second Affiliated Hospital,Harbin Medical University, Harbin Heilongjiang 150086, China [;The relationship between nm23-H_1 gene expression and lymph node metastasis of the esophageal squamous cell carcinoma[J];中国急救医学;2000-01
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【Secondary Citations】
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1 Tu Yunzhong;Dai Anbang;Guo Liyi,et al.(the First Affiliated HOspital of Jiangxi Medical College,Nanchang,330006);Correlation between Expression of p21ras among Colorectal Adenocarcinomas and Staus of Lymph Node Metastasis[J];实用癌症杂志;1996-02
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