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Clinic significance of plasma D-dimer in patients with acute ischemic coronary syndrome

CHEN Shu-yan,ZHANG Jian-jun,WANG Shu-xiang,et al.Department of Cardiology,Xinhua Hospital,Shanghai Second Medical University,Shanghai 200092,China [  
Objective To observe the changes of plasma D-dimer in patients with acute ischemic coronary syndrome and explore the clinic significance.Methods The plasma D-dimer content were determined by ELISA in 21 acute myocardial infarction(AMI group),19 unstable angina pectoris(UAP group),24 stable angina pectoris(SAP group)and 20 normal(control group).Result The plasma D-dimer content in AMI group and UAP group is higher than that in SAP group and control group( P 0 001; P 0 001; P 0 05; P 0 05).The plasma D-dimer content in AMI group is significantly higher than that in UAP group( P 0 01).However,there was no significantly difference between SAP group and control group( P 0 05).Conclusion Plasma D-dimer content may be considered as an marker for the early diagnosis of AMI and has some value in distinction UAP with SAP. [
【CateGory Index】: R541.4;R446.61
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