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《CHINESE JOURNAL OF CRITICAL CARE MEDICINE》 1999-01
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Expression of platelet endothelial cell adhension molecule-1 mRNA in lung with acute lung injury

Wang Jianchun,Mao Baoling,Qian Guisheng Institute of Respiration Medicine, Xinqiao Hospital,Third Military Medical University, Chongqing 400037  
Objective To explore the changes of platelet endothelial cell adhension molecule-1(PECAM-1)mRNA expression and its potential functions in lung with acute lung injury.Methods We measured PECAM-1 mRNA in rat lung with ALI induced by lipopolysaccharide by dot-blot hybridization.Results Normal rat lung expressed PECAM-1 mRNA in higher level, expression of PECAM-1 mRNA was down-regulated early but restored that level in normal rat at 6 hour post-injury in lung.Conclusion Normal lung expresses PECAM-1 mRNA in higher level. PECAM-1 maybe involve in pathogenesis of ALI. [
【CateGory Index】: R655.302
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【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Cai Qinchao,Wang Qonghua,Wu Yunzhi(Department of Biochemistry,Anhui College of TCM,Hefei,230038);PRELIMINARY OBSERVATION ON ENDOCRINE FUNCTION OF VASCULAR ENDOTHELIUM IN BLOOD STASIS PATIENTS[J];JOURNAL OF ANHUI TRADITIONAL CHINESE MEDICAL COLLEGE;1998-02
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【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 WEI Zairong,WANG Yuming,LUO Dan,YOU Xiaojun,WANG Dali,SUN Guangfeng,WANG Bo.Department of Burn and Plastic Surgery,Affiliated Hospital of Zunyi Medical College,Zunyi Guizhou,563003,P.R.China.;EFFECT OF LOW-DOSE CYCLOPHOSPHAMIDE ON THE APOPTOSIS OF LUNG PARENCHYMA CELLS IN THE EARLY SEVERE BURN STAGE IN RATS[J];Chinese Journal of Reparative and Reconstructive Surgery;2008-12
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