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《Journal of Jiangsu University(Medicine Edition)》 2012-02
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Preparation and characterization of mesoporous silica SBA-15-supported molecularly caffeine-imprinted polymers by surface molecularly imprinting technique

WU Yun1,GE Yan-ru1,PAN Ru1,FU Wen-yan1,YAN Yong-sheng2,QI Xue-yong2(1.School of Pharmacy,2.School of Chemistry and Chemical Engineering,Jiangsu University,Zhenjiang Jiangsu 212013,China)  
Objective: The adsorption behavior of the caffeine molecularly imprinted polymer for caffeine was investigated.Moreover,the imprinted polymer was applied for selective extraction of caffeine from tea.Methods: A novel molecularly imprinted polymer was prepared with caffeine as template and modified ordered mesoporous silica SBA-15 as carrier based on surface molecularly imprinting technique.The prepared polymer was characterized by the scanning electron microscopy.The adsorption behavior of the adsorbent for caffeine was investigated using batch experiments.In addition,these imprinted polymers were applied for selective extraction of caffeine from tea.Results: The optimum acidity was around pH 7.0 and the imprinted polymer exhibited fast kinetics and high adsorption capacity for caffeine.Caffeine adsorption process onto MIPs followed the Freundlich adsorption isotherm and the Pseudo-second-order kinetic model.Furthermore,these imprinted polymers could extract caffeine from tea effectively.Conclusion: MIT looks forward to be used as the materials for extraction of caffeine from tea.
【Key Words】: surface molecularly imprinted polymers SBA-15 caffeine adsorption extraction
【Fund】: 江苏大学高级人才基金资助项目(10JDG095);江苏大学百项本科生创新计划资助项目(1201290014)
【CateGory Index】: R943
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【References】
Chinese Journal Full-text Database 1 Hits
1 HAN Guang-min1,SHEN Mao-yan2,LIU Yan-xia3(1.Rizhao Hospital of TCM,Rizhao 276800,China;2.Fuling Center Hospital of Chongqing City,Chongqing 408000,China;3.Rizhao Donggang MCH station,Rizhao 276800,China);Application of Molecular Imprinting Technique on Separation and Purification Components in Traditional Chinese Medicine[J];Food and Drug;2013-04
【Co-references】
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1 LE Kang,FU Ting-ming,GUO Li-wei*(Research Institute of Chinese Medicine,Nanjing University of Chinese Medicine,Nanjing,Jiangsu,210029 P.R.China);Prepartion of TanshinoneⅡA imprinted polymer and application in separation of active ingredient in salvia extracts[J];West China Journal of Pharmaceutical Sciences;2009-05
2 HUANG DanDan,LI Li,YIN YongGuan & ZHU QuanHong College of Traditional Chinese Medicine,Southern Medical University,Guangzhou 510515,China;Synthesis of molecularly imprinted polymers for the application of selective clean-up vinblastine from Catharanthus roseus extract[J];Scientia Sinica(Chimica);2010-06
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7 LIU Shao1,2,3,LI Xin-zhong1,2,LEI Peng1,2,HONG Li-xia2(1.Department of Pharmacy,Xiangya Hospital,Central South University,Changsha 41008;2.School of Pharmacy,Central South University,Changsha 410083;3.Research Center of Modernization of Chinese Medicines,Central South University,Changsha 410083);Preparation of molecular imprinted polymer of neferine[J];Central South Pharmacy;2010-08
8 JIANG Yi-fan1,LI Jin-jin2,ZHONG You-quan1,LUO Gang1,MA Xing-xia1,YIN Xiao-ying1(1.Jiangxi University of Traditional Chinese Medicine College of Pharmacy,Nanchang 330004,China;2.Jiangxi Guoyao Pharmaceutical Co,Ltd.,Nanchang 330022,China);Study on Targeted Separation of Atractylenolide Ⅲ from Traditional Chinese Herbs by Molecularly Imprinted Solid Phase Extraction[J];Chinese Pharmaceutical Journal;2012-13
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