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《Chinese Journal of Antibiotics》 2010-01
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Ceftaroline, a new cephalosporin

Meng Xian-min1,Yao Xiao-ying1,Xu yin1,Zhou Xiao-hua1 and Zhang Yong-Xin2(1 Public Health Clinical Center affiliated to Fudan University,Shanghai 201508;2 Huashan Hospital,Shanghai 200040)  
Ceftaroline(CPT)is a novel,parenteral,broad-spectrum cephalosporin exhibiting strong bactericidal activity against gram-positive organisms,including methicillin-resistant Staphylococcus aureus(MRSA),multidrug-resistant Streptococcus pneumoniae(MDRSP) and vancomycin-resistant Enterococcus faecalis(VRE),as well as common gram-negative pathogens.CPT also has a lot of good profiles such as better safety and tolerability,predictable pharmacokinetics etc.The agent is currently in phase Ⅲ development and can be used for the treatment of MRSA and mixed infections.
【CateGory Index】: R978.1
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