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《Chinese Journal of Antibiotics》 2010-01
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Rational selection of polymyxin B-producing strain

Zhu Xiao-hong1,Zhu Xiao-hui and Wei Wei(Jiangsu Institute of Microbiology Co.Ltd.,Wuxi 214063)  
A colistin producing strain Bacillus polymyxa JSIM-211 was treated by UV,then the mutants which can grow on the minimal culture medium without phenylalanine were obtainend.The stable mutant was treated by UV again,the new mutants which can not grow on the minimal culture medium without tyrosine were isolated.After screening by shaking flask culture,the fermentation of polymyxin B of the mutants was checked out.A specific strain which can accumulate polymyxin B was selected.
【CateGory Index】: Q93
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