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《Chinese Journal of Antibiotics》 2010-01
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Preparation and determination of the content and entrapment efficiency of gemcitabine hydrochloride liposome

Huang Jun-qin and Kong Li-wen(Shanghai Pharmaceutical Science & Technology Development Co.,Ltd.,Shanghai 201203)  
Gemcitabine hydrochloride liposome was prepared through a method of Reverse-phase evaporation,and a HPLC method for the determination of the content and entrapment efficiency of gemcitabine hydrochloride liposome was established.It was showed that the prepared gemcitabine hydrochloride liposome was well-distributed with a spherical shape.The average entrapment efficiency of the liposome was 81.2%,and the average size was 187.5 nm.
【CateGory Index】: R943
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