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《Journal of the Graduate School of the Chinese Academy of Science》 1990-02
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THE LOADING SITE OF CARBOXYL ANION ON CONDENSATION CENTER OF FATTY ACID SYNTHETASE

Tian Weixi(Graduate School, Academia Sinica; National Laboratory of Biomacromoleculcs, Institute of Biophysics, Academia Sinica)  
The inactivation kinetics of fatty acid synthctase(FAS) by modification of six SH reagents has been studied. It is found that the type of kinetics, the specificity of modification and protection by Salt or NADPH, are decided only by the carboxyl anion in reagent. It has been suggested that a carboxyl anion loading site exist in condensation center of FAS. This site is very likely the loading site of malonyl which contains a carboxyl anion, and is essential to condensation.
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【Co-references】
Chinese Journal Full-text Database 8 Hits
1 ZHOU Chang-hai~1,TANAKA Kei-ichi~2 (1.School of Biological and Agricultural Engineering,Jilin University,Changchun 130022,China 2.Graduate School of Agriculture,Hokkaido University,Sapporo 060-0809,Japan);Research on the fatty acid synthetase activity and the fatty acid synthetic method of the meat-type ducks[J];Journal of Northeast Normal University (Natural Science Edition);2004-03
2 WU Miao-zong,CAI Hui-yi(Feed Science Institute of CAAS,Beijing 100081,China);RESEARCH ADVANCES IN TRYPTOPHAN-NIACIN RELATIONSHIP IN ANIMAL NUTRITION[J];Acta Zoonutrimenta Sinica;2002-02
3 Lin Hong Zhao Wanli Huang Fanmei (Dept. of Anim. Sci. Jiangsu Agric. Coll., Yangzhou 225009);STUDY ON THE RELATIONSHIP OF ABDOMINAL FAT AND NADPH GENERATING ENZYMES[J];;1997-01
4 Tian,Wei-xi;Jiang,Ruo-fan;Wu,Hai-bin;Shi,Yan-hong;Wang,Yi-huang(Graduate school of Academia Sinica, Beijing 100039)(National Laboratory of Biomacromolecules, Institute of Biophysics, Academia Sinica, Beijing 100101);The Substrate Inhibition By NADPH And Kinetics Of Fatty Acid Synthase From Duck Liver[J];;1994-04
5 Tian Weixi Liang Qi Qu Baohe Xiao jian(Graduate school, Academia Sinica; National Laboratory of Biomacromlecules, Institute of Biophysics, Academia Sinica);THE INHIBITION EFFECT OF CARBOXYLATES ON FATTY ACID SYNTHETASE[J];Acta Biophysica Sinica;1992-01
6 Xiong Wenzhong 1,Yang Feng 2,Zhou Anguo 2 (1 College of Animal Science,Fujian Agricultural University,Fuzhou 350002; 2 Animal Nutrion Research Insitute,Sichuan Agricultural University,Yaan 625014);STUDY OF REGULATION OF EXOGENOUS RECOMBIANT SOMATOTROPIN ON FAT METABOLISM IN DIFFERENT CROSS—FINISHING PIGS[J];Chinese Journal of Animal and Veterinary Sciences;2001-01
7 Zhu Zeyuan,Shen Aihua and Bao Chenyu (The Institute of Animal Science and Veterinary Medicine, Jiangsu Academy of Agricultural Sciences,210014);The Effects of Dietary Niacin Levels on Growth Performance and Lipid Metabolism at Later Stage of Ducklings[J];ANIMAL HUSBANDRY & VETERINARY MEDICINE;1999-03
8 Wen Jie; Wang Hemin(Institute of Animal Science, Chinese Academy of Agricultural Sciences,Beijing 100094);EFFECT OF NIACIN ON GROWTH PERFORMANCE AND LIPID METABOLISM OF BROILERS[J];SCIENTIA AGRICUTURA SINICA;1995-03
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 RUAN Dong,ZHOU Guilian,JIANG Shouqun(Key Laboratory of Animal Nutrition and Feed(South China)of Ministry of Agriculture,Institute of Animal Science,Guangdong Academy of Agricultural Sciences,Guangzhou,Guangdong 510640);Study on Niacin Requirement of Yellow-feather Broiler Chicks at 1 to 21 Days Age[J];China Poultry;2010-14
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