Glycobiology-Essential for Discovery of Gene's Function
Jin Cheng (State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences,Beijing 100080)
This paper overviews the significance, advances and future direction in the glycobiology field. Special emphasis is given to cell cell adhesion which is mediated by the interaction between carbohydrates and carbohydrates binding proteins (CBP). The roles of carbohydrates in the folding of nascent polypeptides, immune system, and cellular signal transductions are also reviewed. The scope also covers carbohydrates in infections, carbohydrates in diseases,and chemical synthesis/structural analysis of carbohydrates. Finally,the features and future directions of glycobiological research are pointed out by the author.