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《Chinese Journal of Practical Pediatrics》 2008-01
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Curative effect of cattle encephalon glycoside and ignotin injection on neonatal hypoxic-ischemic encephalopathy

QIN Xuan-guang,ZHU Hong-bin,ZHANG Feng-xian,et al.Department of pediatrics,Beijing Chaoyang Hospital Affiliated of Capital University of Medical Sciences,Beijing 100020,China  
Objective To observe curative effect of cattle encephalon glycoside and ignotin injection (GM1 made in China) on neonatal hypoxic-ischemic encephalopathy(HIE).Methods 70 cases neonates with HIE were randomly divided into two groups:GM1 treated group (n=36) and nicholin or fructose-1,6-diphosphate(FDP) treated control group(n=34).The recover time of abnormal neurological symptoms and signs and the score of neonatal behavioral neurological assessment(NBNA) was evaluated in acute phase of HIE.Results The recover time of abnormal neurological symptoms and signs and the score of NBNA there wasn't significant difference between GM1 treated group and control group (P0.05).Conclusion GM1 administ ration has early benefit to the patients with HIE.
【CateGory Index】: R722.1
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1 Wang Lingxiao;Zheng Ximing;Zhumadian Central Hospital;;Variation and clinical significance of serum IL-1β,IL-6 and TNF-α in the neonatal hypoxic-ischemic encephalopathy[J];中国实用医刊;2017-02
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