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《Chinese Journal of Practical Pediatrics》 2012-01
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Clinical features of early preterm infants,late preterm infants and full term infants with respiratory distress syndrome

XU Fa-lin,BAI Qiong-dan,ZHUANG Fang-li,DUAN Jia-jia.Department of Neonatology,the Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China  
Objective To investigate the different clinical characteristics of neonatal RDS with various gestational ages and to provide a new basis for clinical therapy.Methods A total of 963 cases of RDS infants in the Third Affiliated Hospital of Zhengzhou University from Jan.2006 to Dec.2010 were divided into early preterm infants group( 34 weeks,679 cases),late preterm group(34 ~ 37 weeks,204 cases),and full-term group(≥ 37 weeks,80 cases)according to gestational age respectively,and the general situation,risk factors,clinical condition,prognosis and complications in each group were analyzed.Results There was an increasing tendency for the incidence of RDS,which predominantly happened in the early preterm infants.What's more,the prevalence of RDS in late preterm infants and term infants was increased.The proportion of RDS in the male was higher than the female(P 0.05),especially when the gestational ages and weight were greater.The antenatal use of glucocorticoid in full-term RDS infants was significantly lower than the preterm infants.The risk factors of preterm RDS were closely relevant to the rupture of membranes,placental abnormalities,women with pregnancy-induced hypertension,while those of the full-term newborns with RDS were frequently related to selective cesarean section.The time window of the diagnosis of the full-term RDS was later than that of the preterm RDS.The application of mechanical ventilation to full-term RDS infants was significantly more than to the preterm infants while the clinical cure rate was significantly higher(P 0.05),but the mortality rate was not different,and more pulmonary infection and pneumothorax occured in full-term group consequently.Conclusion The incidence of neonatal RDS is increasing yearly and the prevalence of RDS in late preterm infants and term infants increase.The different clinical characteristics between the preterm RDS and full-term RDS lie in the morbidity,sex ratio,risk factors,clinical characteristics,treatment response and complications etc.The gestational age factor should be considered to diagnose and treat RDS.The full-term RDS which are characterized by relatively late onset and complication of pneumothorax,has a close relation to elective cesarean section and infection,should be paid more attention to in the future.
【Fund】: 河南省医学科技攻关项目(200803065)
【CateGory Index】: R722.1
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 XU Fa-lin,Shrestha Him Kumar,CHENG Xiu-yong(Department of Neonatology,the Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China);Therapeutic Effect of Antenatal Corticosteroids and Postnatal Pulmonary Surfactant on Neonatal Respiratory Distress Syndrome[J];Journal of Applied Clinical Pediatrics;2008-16
【Co-citations】
Chinese Journal Full-text Database 9 Hits
1 Chen Wendan;Nursing care of twin pregnancy patients after one fetus abortion at late pregnancy[J];Journal of Nursing Science;2011-06
2 Hu Xiaojing,Zhang Yuxia,Chen Chao,GuYing,Cao Yun;Early supportive care for two premature infants with extremely low birth weight[J];Journal of Nursing Science;2011-21
3 CHEN Li-juan,CHENG Xiu-yong(Neonatal Intensive Care Unit,the Third Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China);Influence of Single and Multiple Course Dexamethasone on Brain Development of Preterm Infants[J];Journal of Applied Clinical Pediatrics;2009-06
4 WANG Yan1,KONG Xiang-yong2,FENG Zhi-chun2(1.Department of Pediatrics,Zhujiang Hospital Affiliated to Southern Medical University,Guangzhou 510080,Guangdong Province,China;2.Beijing Military General Hospital Affiliated Bayi Children Hospital,Beijing 100700,China);Therapeutic Effect of High Frequency Oscillatory Ventilation on Premature Infants with Respiratory Distress Syndrome[J];Journal of Applied Clinical Pediatrics;2009-14
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8 SU Hong-mei,MAO Xin-li,YUAN Hui-rong,et al.(Luogang District Maternal and Child Health Care Hospital,Guangzhou,510730,Guangdong,China);Analysis on Low Birth Weight Infants in Luogang District of Guangzhou from 2008 to 2009[J];Preventive Medicine Tribune;2010-07
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