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《Chinese Journal of Practical Pediatrics》 2012-01
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Comparison of neonatal critical illness score with score for neonatal acute physiology,perinatal extension,Version II in predicting mortality risk in critically ill neonates

QIU Ru-xin,YANG Li.Department of Pediatrics,School of Medicine,Southeast University,Nanjing 210009,China  
Objective To compare the advantages of critically ill neonates mortality risk prediction between neonatal critical illness score and score for neonatal acute physiology,perinatal extension,Version II(SNAPPE-II)and to research for the better neonatal disease severity scoring system feasible for use in our country.Methods The 525 neonates,who were in neonatal intensive care unit(NICU)from Jan 2008 to Dec 2008 in the Zhongda Hospital affiliated to Southeast University,were scored by NCIS and SNAPPE-Ⅱ simultaneously.According to the scores the patients were divided into three groups(very critical group,critical group,non-critical group),and mortality rates were compared in each group.At the same time we drew the receiver operating characteristic curve(ROC)and counted out their areas under the ROC curves to observe the specificity and sensitivity of two scoring systems in predicting the risk of death in critically ill neonates.Results The comparison between NCIS and SNAPPE-Ⅱscore:the differences were not statistically significant in mortality between the non-critical and the very critical subgroups(P 0.05);the difference between the two critical subgroups was statistically significant in mortality(P 0.05);the area under the ROC curve(AUC):NCIS 0.934,SNAPPE-Ⅱ0.926.The differences were not statistically significant in AUC between NCIS and SNAPPE-Ⅱ.Conclusion SNAPPE-Ⅱcan predict mortality risk in critically ill neonates earlier and more accurate and clinical application is easy.SNAPPE-Ⅱshould be used generally.NCIS's ability to distinguish critically ill newborns is better than SNAPPE-II,but cannot guide the clinical decision-making.
【CateGory Index】: R722.1
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