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《中山医科大学学报》 1991-03
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EFFECTS OF 3,6-DIMETHAMIDODIBENZO PYRIODONIUM (I-65)ON THE BRAIN IMPAIRMENT DUE TO ACUTE CEREBRALISCHEMIA AND REPERFUSION

Li Xiangzhi HongJixun Chen Yici (Department of Anatomy)  
Intensive attention was recently payed to brain impairment due to acute cerebral ischemia and reperfusion, this paper reports on cortex somatosensory evoked potentials (SEPs), light microscope and electron microscope have been used to study the effect of calcium channel blocker I -65 on the brain impairment due to acute cerebral ischemia and reperfusion. The results suggest that 1-65 can protect electric activily of cerebral cortex neurons and ultrastructure of mitochondria and RER of neurons during acute cerebral ischemia and reperfusion. The mechanism may be blocking Ca2+ channel selectively so that preventing the increase of concentrations of Ca2+ within neurons.
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【Citations】
Chinese Journal Full-text Database 1 Hits
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【Co-citations】
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