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《中山医科大学学报》 1992-01
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IMMUNOCYTOCHEMICAL STUDY WITH ANTI-MUSCLE ACTIN ANTIBODY (HHF35) ON MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY IN RATS

Fu Chenzhong Song Yixuan Xue Guanhua Zhu Jiazhen Bi Qiming ( Department of Forensic Pathology )  
Myocardial ischemia and reperfusion in 16 anaethetized SD rats, of which, 8 cases were pretreated with morphine (5mg/kg, i. p.) for preventing arrhythmias, were studied immunocytochemically with anti-muscle actin specific monoclonal antibody (HHF35). Parallelly, 8 cases of sham-operated rats were used as control. With HHF35 ABC im-munocytochemical method, the area of myocardial ischemia and reperfusion injury ( without morphine) showed decrease or absence of staining, large areas of staining loss were also seen; but in the group with morphine, only small foci of staining absence were shown. The myocardium in control animals showed evenly distributed positive staining. No change were seen with HE staining in all groups. The results obtained with HHF35 staining support its important value in studying on myocardial reperfusion injury, and indicate that the degree of myocardial damage may be related to the arrhythmias in myocardial reperfusion injury.
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Guan Dawei;Coronary Artery Injury to Postischemic Canine Myocardium.[J];法医学杂志;1990-04
【Co-citations】
Chinese Journal Full-text Database 2 Hits
1 Fu chenzhong Song Yixuan Xue Guanhua Zhu Jiazhen Bi Qiming Department of Forensic Pathology,Sun Yat Sen University of Medical Sciences,Guangzhou,510089;IMMUNOCYTOCHEMICAL STUDY WITH ANTI-MUSCLE ACTIN ANTIBODY(HHF_(35))ON MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY IN RATS[J];中国法医学杂志;1993-04
2 Fu Chenzhong Song Yixuan Xue Guanhua Zhu Jiazhen Bi Qiming ( Department of Forensic Pathology );IMMUNOCYTOCHEMICAL STUDY WITH ANTI-MUSCLE ACTIN ANTIBODY (HHF35) ON MYOCARDIAL ISCHEMIA AND REPERFUSION INJURY IN RATS[J];中山医科大学学报;1992-01
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