Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《中山医科大学学报》 1992-01
Add to Favorite Get Latest Update

DISTRIBUTION OF BASEMENT MEMBRANE COMPONENT IN HUMAN HEPATOCELLULAR CARCINOMA AND ITS XENOGRAFT IN NUDE MICE

Ouyang Nengtai Zhou Muheng Dong Jun ( Department of Pathology )  
Authors described the immunohistochemical localization for components of the basement membrane (BM), fibronectin (FN), collagen type Ⅳ (CollⅣ ) and laminin (LAM), in 15 hepatocellular carcinoma (HCC ) and 3 human HCC xenografts in nude mice. The results indicated that: 1. The above-mentioned BM components became irregularly distributed and their quantity was decreased in the human HCC xenografts of nude mice, but the morphological structure of the carcinoma was not changed. 2. There was a continuous BM components capsule, surrounding the xenografts of nude mice, while it could not be seen in the human HCC. This might be responsible for the failed invasion of the xenografts. 3. The pericellular staining for FN and Coll Ⅳ were found in the HCC xenografts of nude mice. This suggests that the FN and Coll Ⅳ might be synthesized, at least in part by hepatocellular carcinoma cells.
【Fund】: 高校博士点科研基金资助课题
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Xue Kexuen,Gao Jin and Dong Huayi(Institute of Basic Medical Sciences, Beijing)Jing Shaoliang, Chen Shaochun and Zou Gangyan(Experimental Animal Research Centre, Beijing);Comparative Observation on Invasiveness in Nude Mice after Transplantation of Human Pulmonary Adenocarcinoma Cell Line into Different Sites[J];中国医学科学院学报;1986-02
2 Tang Zhao-you et al;HUMAN HEPATOCELLULAR CARCINOMA (HCC) MODEL IN NUDE MICE-ESTABLISHMENT OF HCC TISSUE MODEL AND ITS APPLICATION IN EXPERIMENT RESEARCH[J];肿瘤;1986-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LI Yan, TANG Zhaoyou, YE Shenglong, LIU Yinkun, CHEN Jie, XUE Qiong, HUANG Xiaowu, CHEN Jun, BAO Weihua, YANG Jiong, GAO Dongmei. Liver Cancer Institute and Zhong Shan Hospital of Fudan University, Shanghai, 200032, China;Establishment of human hepatocellular carcinoma cell line with spontaneous pulmonary metastasis through in vivo selection[J];中华医学杂志;2002-09
2 Shi Yansheng, Geng Zhixian, Zhong Da wei, et al (Laboratory Animal Center Academy of Military Medical Sciences, Beijing 100071,China);Study on the Xenograft of two Human Carcinoma Cell Lines in SCID and BALB/c nude Mice[J];中国实验动物学杂志;2000-01
3 Zhu Yuanxi; Hao Xishan; Sun Hut; et al. (Tianjin Cancer Institute Hospital,Tianjin 300060) [;Experimental Study on the Treatment of Human Hepatocarcinoma in Nude Mouse by Beta-carotene Combined with Adriamycin[J];中国肿瘤临床与康复;1999-05
4 Fu Hong Mei, Lu Yuan.Department of Clinical Laboratory, Hua Shan Hospital, Shanghai Medical University, Shanghai 200040;Analysis of N liked sugar chain structures of ALP from human liver cancer tissue.[J];上海医学检验杂志;1999-03
5 Xue Kexun; Gao Jin et al. Institute of Basic medical Sciences Institute of Laboratory Animal SciencesChinese Academy of Medical Sciences,Beijing[;Study on Invasion and Metastasis of Human Tumor Cells After Subcutaneous Transplantation of Tumor Cells into Different Sites of SCID Mice[J];实验动物科学与管理;1996-03
6 Bai Shaohuai;Zhang Xuanbo;Xie Congyi;Hou Shixiang;Zhang Zhirong;Liao Gongtie Center of Lab Animals Department of Pharmeceutics;A Model off Orthotopic Transplantation of Human Hepatoma Established in Nude Mice Tumor Inhibition Studies[J];华西医科大学学报;1993-04
7 Liu Yuqin, (Institute of Basic Medical Sciences, CAMS and PUMC, Beijing);Comparative Study and Morphometrical Analysis of the In Vivo Invasiveness of Mouse Lung Adenocarcinoma Variants with Different Metastatic Potentenials[J];中国医学科学院学报;1993-05
8 Ouyang Nengtai Zhou Muheng Dong Jun ( Department of Pathology );DISTRIBUTION OF BASEMENT MEMBRANE COMPONENT IN HUMAN HEPATOCELLULAR CARCINOMA AND ITS XENOGRAFT IN NUDE MICE[J];中山医科大学学报;1992-01
9 Xue Kexun (Institute of Basic Medical Science, Beijing);Influence of Site and Method of Implantation on Growth and Invasion of Human Lung Adenocarcinoma in Nude Mice[J];中国医学科学院学报;1991-06
10 Xue Kexun, Gao Jin, Dong Huayi, Jing Shaoliang, Chen Shaochun and Zou Gangyan(Institute of Basic Medical Sciences, Beijing) Experimental Animal Research Centre, Beijing;Establishment of Transplantable Human Lung Adenocarcinoma Cell Line in Nude Mice and Observation of Its Biological and Ultrastractural Characteristics[J];中国医学科学院学报;1987-05
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Xue Kexun, Gao Jin, Li Baogui, Dong Huayi (Departraent of Pathology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing);THE OBSERVATION OF ULTRASTRUCTURAL CHARACTERISTICS OF A TRA NSPLANTABLE CANCER OF UTERINE CERVIX (U 27) OF MICE AND ITS INVASIVENESS AFTER INTRAMUSCULAR IMPLANTATION[J];解剖学报;1984-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved