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《Journal of Sun Yat-sen University (Medical Sciences)》 1993-01
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THE LEVELS OF THE MATERNAL SERUM PRL AND E_2 AND THEIR RELATIONSHIP DURING PREGNANCY IN NORAL WOMEN AND IN THE WOMEN WITH PROIACTINOMA

Wen Yanping Liang Guishang (Department of Obstetrics and Gynecology First Affiliated Hospital)  
This study comprised of 180 normal pregnancies and 8 patients with prolactinoma who became pregnant after CB-154 treatment. The results are as follows: 1) Serum PRL in both groups was gradually elevated till the third trimester gestation. The PRL concentrations were significantly higher in prolactinoma group than those in normal group during 6th-l6th weeks of gestation. 2) Serum E2 levels increased with developing of gestation "and no statistical differences were observed between the two groups. 3) Significant correlations were found between serum PRL, E2 levels and the weeks of gestation, respectively. 4) The correlation between serum PRL and E2 concentration was significant only in the second trimester of normal group whereas it was significant in first trimester in prolactinoma group. These results suggested that serum PRL and E2 concentrations were increasing gradually during the whole period of gestation, but their correlation was significant only in some stages of gestation. It seems that E2 was the main stimulator of PRL-secretion, however it was not the only modulator during pregnancy. That the serum levels of PRL and E2 showed no remarkable differences between two groups indicats that prolactinoma does not affect E2-production in the placental and that PRL secretion is autonomous. Hence, we deduce that women with prolactinoma would be well being during their pregnancy and that periodic PRL assay is one of the reliable monitoring index.
【Fund】: 国家自然科学基金;; 部分863高技术科学基金资助项目
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【References】
Chinese Journal Full-text Database 1 Hits
1 Zhang Cheng; Liu Zhoulin; Liang Xiulin;Pan Xibang (Department of Neurology First Affiliated Hospital of Sun Yat-sen University of Medical Sciences. Guangzhou 510089);UCHENNE MUSCULAR DYSTROPHY[J];ACADEMIC JOURNAL OF SUN YAT-SEN UNIVERSITY OF MEDICAL SCIENCES;1994-01
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 YAN Zhen and SU Chen-Zhi Department of Biochemistry;Expression of Duchenne muscular dystrophy cDNA fragment in E.coli and preparation of its antiserum[J];Journal of The Fourth Military Medical University;1993-04
2 Wang Ning; Yu Long; Murong Shenxing; et al(Department of Neurology, Fujian Medical College, Fuzhou 350005);A Study on Gene Diagnosis in Pseudo-Hypertrophic Muscular Dystrophy I.Analysis of Molecular Deletion in 5’Region of Dystrophin Gene[J];;1994-03
3 Wang Ning;Yu Long;Murong Shenxing;et al(Department of Neurology,FuJian Medlcal College,Fuzhou,350005);A Study on Gene Diagnosis in DMD/BMD Ⅱ.Analysis of Deletions or Duplications in the Central Mutate Portion or Dystrophin Gene[J];;1995-02
4 Wang Ning;Yu Long; Wu Zhiying,et al( Department of Neurology, Fujian Med-ical College,Fuzhou 350005.);Detection of point mutation in DMD/BMD patients without deletion using PCR amplifica-tion and SSCP analysis[J];JOURNAL OF CLINICAL NEUROLOGY;1995-02
5 Yu Long (Sun Yatsen Medical University,Guangzhou);A noninvasive study on heart volume,cardiac cavity and ventricular wall in Duchenne muscular dystrophy[J];Journal of Clinical Cardiology;1989-01
6 WEI Yong; CAI Ti; WU Xiao-Hui; KANG Yi-Binand CHAI Jian-Hua(Human Genome Laboratory, Institute of Genetics Fudan University, Shanghai, 200433);Construction and Large-scale Mapping of a 3. 5 Mb YAC Contig Spanning Human Chromosome Xp 21. 1-21 .3[J];ACTA BIOCHIMICA ET BIOPHYSICA SINICA;1995-06
7 Hua Xiao-yun; XuMin-hua; Lin Qun-di et al. (Sun Yat-sen Universityof Medical Sciences, Guangzhou, 510089);Preuatal diagnosis of Duchenne's musculardystrophy fetus at risk[J];Chinese Journal of Obstetrics And Gynecology;1994-07
8 Wang Jiang, Shen Dingguo, Liu Hong. Division of neuromuscular disorders, Chinese PLA General Hospital, Beijing 100853;Detection of gene deletions in 134 cases of Duchenne and Becker muscular dystrophy with the technic of two step multiplex polymerase chain reaction (PCR)[J];CHINESE JOURNAL OF NEUROLOGY;1997-05
9 Yan Zhen;Su Chenzhi(Department of Biochemistry,the Fourth Military Medical University,Xi'an 710032);PREPARATION OF SPECIFIC ANTISERUM ANTI 5-7 AGAINST DYSTROPHIN[J];CHINESE JOURNAL OF MEDICAL CENETICS;1994-02
10 Hu Donggui;Hua Xiaoyun;Du Chuanshu, et al.(Department of Medical Genetics.Sun Yat-sen University of Medical Sciences,Guangzhou 510089);APPLICATION OF REVERSE TRANSCRIPTION AND NESTED PCR IN THE GENE DIAGNOSIS OF DMD/BMD CARRIERS[J];CHINESE JOURNAL OF MEDICAL CENETICS;1995-04
【Secondary References】
Chinese Journal Full-text Database 4 Hits
1 OUYANG Sheng-rong,Li Yuan-yuan,Liu Zhuo,Wang Li-wen,WU Jian-xin(Peking University Teaching Hospital-Capital Institute of Pediatrics,Beijing,100020,China);Bioinfomatics Analysis of the Relationship between Re-initiation of Translation and BMD in Dystrophin with Exons3-7 Deletion[J];Progress in Modern Biomedicine;2009-15
2 CHEN Song-lin,LIANG Ying-yin,FENG Shan-wei(Department of Neurology,The First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,China.);Mechanism of DMD with gene defect and change of protein structure[J];Chinese Journal of Pathophysiology;2008-07
3 Cai Hong,Wang Liwen,Wu Jianxin,et al.Capital institute of Pediatrics,Beijing 100020, China;A study on correlated gene of childhood Duchenne muscular dystrophy[J];Chinese Journal of Practical Pediatrics;2002-07
4 YUAN Wo-liang1,NIE Ru-qiong1,LIU Ying-mei1,ZHOU Shu-xian1,ZHANG Meng3,WANG Jing-feng1,TAO En-xiang2 ( 1. Cardiovascular Department of The Second Affiliated Hospital,2. Neurology Department of The Second Affiliated Hospital,3. Pathology Department of Zhongshan Medical School,SUN Yat-sen University,Guangzhou 510120,China );Clinical and Pathological Characteristics of a Limb-girdle Muscular Dystrophy and Myocardial Impairment Family[J];Journal of Sun Yat-Sen University(Medical Sciences);2007-03
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