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《Journal of Sun Yat-sen University(Medical Sciences)》 2014-01
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Evaluate Auditory Function for OSAHS patients in Xinjiang Uyghur Nationality Via Two Methods

WU Mei;YALIKUN Yasheng;Department of Otorhinolaryngology,The First Affiliated Hospital of Xinjiang Medical University;Department of No.1 Otorhinolaryngology,The People's Hospital in Xinjiang Uyghur Autonomous Region;  
【Objective】 To evaluate whether OSAHS affects auditory function, furthermore, investigate damaged sites and characteristics in Xinjiang Uyghur nationality. 【Methods】 Total of 70 Uyghur adults with OSAHS and 35 healthy Uyghur adults as control group, which were monitored and diagnosed by polysomnography. After that, OSAHS subjects were grouped into mild, moderate and severe degrees. The damage of hearing function for all subjects was evaluated by DPOAE(distortion-product otoacoustic emissions) and ABR(auditory brainstem response) detections. 【Results】 The values of DPOAE(750 to 8 000 Hz) were decreased, difference was statistically significant between OSAHS and control group(P 0.05). Via ABR test, there was statistical significance(P 0.05) between mild-to-moderate OSAHS and control group in the latency of wave I, III and V, the interpeak latency of I-III, IV; In the severe group, wave latency and interpeak latency were significantly longer than control group(P 0.05); Mild-to-moderate group compared with severe one, difference of wave I, III latency and interpeak latency of I-V with statistical significance(P 0.05). Degrees of OSAHS are closely correlated to BMI, obstructive site, snoring index, lowest oxygen saturation, in addition, detected rate of DPOAE and abnormal rate of ABR exist statistical difference(P 0.05). 【Conclusion】 OSAHS can lead to the auditory function damage in Uyghur nationality. Active hearing function of cochlear decline, especially in high frequency hearing loss obviously, accompanied by impairment of central part of auditory nerve and / or the auditory center. DPOAE and ABR detections are necessary to be combined to evaluate hearing function damage among Uyghur OSAHS, which could contribute to screen out early hearing damage and to timely therapeutic intervention.
【CateGory Index】: R764.04
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