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《Journal of Sun Yat-sen University(Medical Sciences)》 2017-01
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Diagnostic Value of MRI Combined TRUS for Prostate Cancer at Different Prostate-specific Antigen (PSA) Levels

SU Guan-yu;MAO Xiao-peng;MO Cheng-qiang;LI Bai-mou;CHEN Xu;ZHUANG Jin-tao;QIU Shao-peng;Department of Urology,The First Affiliated Hospital of Sun Yat-sen University;Department of Urology,Eastern Hospital of the First Affiliated Hospital of Sun Yat-sen University;  
【Objective】To explore the diagnostic value of magnetic resonance imaging(MRI)combined transrectal ultrasound(TRUS)to guide prostate cancer detection at different serum prostate-specific antigen(PSA)levels.【Methods】Totally 278 patients who underwent a systematic biopsy were collected in our hospital from November 2014 to June 2016. Preoperative tests of PSA,MRI,TRUS were performed in all the included patients. According to the PSA level of 4 ~ 10 ng/m L,10 ~ 20 ng/m L,over 20 ng/m L,278 cases were divided into three group of A,B,C. Retrospective analysis was performed within the three groups of diagnostic accuracy.【Results】In Group A,the areas under ROC for MRI+TRUS and TRUS were 0.73 and 0.59,respectively(P = 0.02). In Group B,the areas under ROC for MRI+TRUS and TRUS were 0.68 and 0.56,respectively(P 0.001). In Group C,the area under ROC for MRI+TRUS and TRUS were 0.74 and 0.63,respectively(P 0.001). There is more significant statistical difference in Group B and C.【Conclusion】MRI combined TRUS has higher diagnostic value in cancer detection than TRUS before biopsy between different PSA levels,which Indicates that MRI combined TRUS is an effective method for the improvement of prostate cancer detection.
【Fund】: 国家自然科学基金(81001146);; 广东省科技计划项目(2012B031800033)
【CateGory Index】: R737.25
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【References】
Chinese Journal Full-text Database 1 Hits
1 Wu Yunhong;Wang Lei;Hu Xueping;Li Ding;Urology Surgery, Wuxi Second People's Hospital;Urology Surgery, Huashan Hospital, Fudan University;;Effect of enhanced recovery after surgery(ERAS) on postoperative pain and recovery in patients undergoing laparoscopic radical prostatectomy[J];国际医药卫生导报;2017-20
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1 Yu Luping;Liu Chunlei;Li Qing;Yang Bo;Chen Lili;Liu Shijun;Xu Tao;Department of Urology of Peking University People's Hospital;;The expression of sex determining region Y-box 18 in prostate cancer and its impact on prostate cancer cell function[J];中华泌尿外科杂志;2017-02
2 Chen Yiming;Xu Renfang;Xu Xianlin;Lu Hao;Ding Tao;Fan Min;Zhuang Qianfeng;Chen Zhen;Xing Zhaoyu;He Xiaozhou;Department of Urology,Third Affiliated Hospital of Suzhou University;;The prognostic value of platelet to lymphocyte ratio and neutrophil to lymphocyte ratio in the patients with early castration resistant prostate cancer after androgen deprivation therapy[J];中华泌尿外科杂志;2017-02
3 Zhu Zaisheng;Ye Min;Shi Hongqi;Luo Rongli;Xu Lizhen;Zhou Pengfei;Department of Urology,Jinhua Hospital,Zhejiang University;;Clinical analysis of standardized extended pelvic lymph node dissection in radical prostatectomy[J];中华解剖与临床杂志;2017-01
4 Cui Yanchao;Nursing Department,Anyang Hospital of Traditional Chinese Medicine;;Pelvic floor muscle exercise in different times for uroclepsia patients after radical prostatectomy[J];国际医药卫生导报;2016-02
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