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《ACADEMIC JOURNAL OF SUN YAT-SEN UNIVERSITY OF MEDICAL SCIENCES》 1997-01
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EFFECT OF FAECES TROGOPTERORI EXTRACT ON EXPERIMENTAL GASTRIC ULCER AND GASTRIC SECRETION IN RAT

Cheng Zhi'an Li Qingmin Wang Xiongwen (Department of Traditional Chinese Medicine, Sun Yat sen Memorial Hospital, Sun Yat sen University of Medical Sciences, Guangzhou, 510120)  
Four components from faeces trogopterori (WLZ) extract: WLZ A, B, C,D were isolated for elucidating the protective effect of which on gastric mucosa and identifying the effective principle. Shay model and reserpine model were used. The results showed that the amount of gastric juice, gastric acidity and total secreting acid of WLZ B groups were significantly lower than that of the control group ( P 0.01). The lesion scores of WLZ B groups in both models were significantly lower compared with control groups ( P 0.01). These results indicate that the mechanism by which the WLZ B protect mucosa and prevent ulceration is due to inhibition of the gastric secrection.
【Fund】: 国家自然科学基金
【CateGory Index】: R573.1
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