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《ACADEMIC JOURNAL OF SUN YAT-SEN UNIVERSITY OF MEDICAL SCIENCES》 1997-01
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EVALUATION ON THE EFFECT OF AMINOPHYLLINE ON FETAL DISTRESS

Wang Yunhui Mei Shaofen Ding Hong (Department of Obstetrics and Gynecology, Sun Yat sen Memorial Hospital. Sun Yat sen University of Medical Sciences, Guangzhou, 510120)  
To investigate the effect of aminophylline on fetal distress, sixty cases of pregnancy with fetal distress were devided at random into two groups. In one group(group A), 0.25g of aminophylline combined with 50% glucose was administrated intravenously. In another group (group B), 0.5g of vitamin C, 10mg of vitamin K 1 and 50% glucose were used intravenously. Changes of fetal heart rate, amniotic fluid, blood gas assaying of umbilical veins and newborn Apgar score in two groups were evaluated. Improved heart rate was 79% in group A and 48% in group B after administration of the medicines( P 0.05). Blood pH lower or equal to 7.2 based on blood gas assaying was 25% in group A and 42% in group B. Mean value of PCO 2 was 5.98 kPa in group A and 7.57 kPa in group B ( P 0.01). Newborn Apgar score equal to or lower than 7 in group A (2/30) was significantly lower than that in group B(10/30)( P 0.05). Aminophylline is effective for the resuscitation of intrauterine fetal distress.
【CateGory Index】: R722.12
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