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《Chinese Journal of Gastrointestinal Surgery》 2002-04
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Clinicopathological characteristics and prognosis of patients younger than 40 years with colorectal cancer

WANG Jianping,WANG Lei,YANG Zuli,et al. Department of Gastrointestinopancreatic Surgery,The First Affiliated Hospital, Sun Yat sen University, Guangzhou 510080,China  
Objective To investigate the clinicopathological features and prognosis of patients younger than 40 years with colorectal cancer. Methods The clinicopathological and follow up data of 151 patients younger than 40 years with colorectal cancer from July,1994 to July,2001 were retrospectively reviewed, and compared with that of 465 patients aged 65 and older than 65 years with colorectal cancer. Results Significant differences were found in family history,tumor size,histologic type and differentiation grade. There were no significant difference in Dukes stage,infiltration depth,nodal metastasis were found between these two groups. The 5 year survival rates of younger group and older group were 54 56% and 53 11% respectively (P 0 05). Conclusion There are no significant differences in Duke′s stage and survival rate between two groups, and the age is not the prognostic factor for colorectal cancer.
【Fund】: 广东省科学委员会科技攻关项目(97010)
【CateGory Index】: R735.3
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