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Observation of esomeprazole enteric coated capsules in the treatment of Helicobacter pylori

Su Hongge;Digestion Department of Internal Medicine,Yuzhou City Center Hospital;  
Objective:To observe the clinical effect of esomeprazole enteric capsule in the treatment of Helicobacter pylori.Methods:140 patients with duodenal ulcer who were treated in our hospital from October 2013 to November 2014 were randomly divided into treatment group and control group,two cases in each group,70 cases in each group.In the control group were treated with clarithromycin for treatment,the patients in the treatment group in the control group patients on the basis of the esomeprazole enteric coated capsules for treatment.To observe the treatment results of the two groups of patients.Results:The eradication rate of Helicobacter pylori in treatment group was 70%,the control group was 34.29%,the cure rate was17.14%in treatment group and two in control group(P0.05),and the serum inflammatory factor C- and interleukin 6 were significantly better than those in control group(P0.05).Conclusion:The Esso esomeprazole enteric coated capsule in the treatment of Helicobacter pylori effect significantly,can effectively improve the Helicobacter pylori eradication rate,ulcer healing rate,on inflammatory cytokines in serum C-reactive protein,leukocyte mediated also has obvious effect and adverse reactions less,with high clinical application value.
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