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Evaluation of the clinical significance of detection of carbohydrate antigen 125 in gynecological tumors

Xiong Ziming;Maternal and child health care hospital of Dayi County;  
Objective:To study and discuss the clinical significance of detection of carbohydrate antigen 125(CA125)in gynecological tumors.Methods:80cases of gynecologic benign tumor and 80 cases of gynecologic malignant tumor in our hospital from January 2011 to May 2014 were selected as the research objects,respectively,are set to benign group,malignantgroup;In the same period 80 cases of healthy women,is set to the control group.The average level of serum CA125 in three groups was compared,and the detection rate of CA125 in different levels of benign and malignant groups were compared.Patients in benign group and malignant group were treated with surgery,the expression level of CA125 in the two groups before and after surgery were compared,comparison of serum CA125 levels in patients with recurrent and non recurrentpatients.Results:The expression levels of CA125 in the serum of the three groups were compared,and the differences were statistically significant(P0.05).When the CA125 was less than 35U/ml and 35~70U/ml,the positive rate of the benign group was significantly higher than that of the malignant group(P0.05);When 71~140U/ml,141~280U/ml and CA125 were more than 280U/ml,the positive rate of malignant group was significantly higher than that in benign group(P0.05).Compared with before operation,the expression of CA125 in the two groups was significantly lower(P0.05).Compared with the patients without recurrence,the serum CA125 levels were significantly higher in the two groups(P0.05),the expression level of CA125 in serum of patients with recurrent malignant group was significantly higher than that in benign group(P0.05).Conclusion:Carbohydrate antigen 125 is not only effective in the diagnosis of gynecologic tumors,but also can effectively distinguish between benign and malignant gynecologic tumors,at the same time,can effectively assess the prognosis of patients,with a high diagnostic value and prognostic value.
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