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《Women's Health Research》 2017-06
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Relationship Between Angiopoietin-2 and Vascular Endothelial Growth Factor in the Pathogenesis of Condyloma Acuminatum

Zhou Xing;Lu Hong;Chen Huiyang;Department of Dermatology,Beijing No.6 Hospital;  
Objective:To investigate the effects of angiopoietin-2(Ang-2)and vascular endothelial growth factor(VEGF)expression in condyloma acuminatum tissues and peripheral blood,and the significance of the research two in the pathogenesis of condyloma acuminatum in rats.Methods:Randomly selected 30 cases of patients with condyloma acuminatum,the expression of Ang-2and VEGF protein detected by immunohistochemical method of double antibody sandwich enzyme-linked immunosorbent assay and Ang-2VEGF assay in peripheral blood serum level,and compared with 20 normal controls.Results:Compared with the control group,the expression of condyloma acuminatum lesions of patients with psoriasis Ang-2and VEGF obviously increased(χ~2 respectively.31.04,18.07,P,Ang-2and0.01)were significantly increased in serum VEGF levels(t=3.16,5.56,Pvalue0.05).Conclusion:The expression of Ang-2and VEGF expression in condyloma acuminatum,may promote the formation of blood vessels in condyloma acuminatum and occurrence Development.
【CateGory Index】: R752.5
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